Letter to the Editor regarding 'Unique pharmacodynamic properties and low abuse liability of the µ-opioid receptor ligand (S)-methadone'

M Pappagallo, TR Kosten, CW Gorodetzky… - Molecular …, 2024 - nature.com
We wish to commend Levinstein and colleagues for their contribution to our understanding
of the pharmacodynamic (PD) properties of esmethadone [(S)-MTD] at mu opioid receptors …

Sex-dependent effects of the uncompetitive N-methyl-D-aspartate receptor antagonist REL-1017 in G93A-SOD1 amyotrophic lateral sclerosis mice

M Colognesi, A Shkodra, D Gabbia… - Frontiers in …, 2024 - frontiersin.org
Introduction The pathogenesis of amyotrophic lateral sclerosis (ALS), a fatal
neurodegenerative disease caused by the demise of motor neurons has been linked to …