[HTML][HTML] Designing spatial and temporal control of vaccine responses
Vaccines are the key technology to combat existing and emerging infectious diseases.
However, increasing the potency, quality and durability of the vaccine response remains a …
However, increasing the potency, quality and durability of the vaccine response remains a …
[HTML][HTML] Hypes, hopes, and the way forward for microalgal biotechnology
The urge for food security and sustainability has advanced the field of microalgal
biotechnology. Microalgae are microorganisms able to grow using (sun) light, fertilizers …
biotechnology. Microalgae are microorganisms able to grow using (sun) light, fertilizers …
Transdermal vaccination via 3D-printed microneedles induces potent humoral and cellular immunity
C Caudill, JL Perry, K Iliadis… - Proceedings of the …, 2021 - National Acad Sciences
Vaccination is an essential public health measure for infectious disease prevention. The
exposure of the immune system to vaccine formulations with the appropriate kinetics is …
exposure of the immune system to vaccine formulations with the appropriate kinetics is …
A single immunization with spike-functionalized ferritin vaccines elicits neutralizing antibody responses against SARS-CoV-2 in mice
The development of a safe and effective SARS-CoV-2 vaccine is a public health priority. We
designed subunit vaccine candidates using self-assembling ferritin nanoparticles displaying …
designed subunit vaccine candidates using self-assembling ferritin nanoparticles displaying …
[HTML][HTML] Antimicrobial resistance and recent alternatives to antibiotics for the control of bacterial pathogens with an emphasis on foodborne pathogens
Antimicrobial resistance (AMR) is one of the most important global public health problems.
The imprudent use of antibiotics in humans and animals has resulted in the emergence of …
The imprudent use of antibiotics in humans and animals has resulted in the emergence of …
Synthetic nanoparticles for vaccines and immunotherapy
The immune system plays a critical role in our health. No other component of human
physiology plays a decisive role in as diverse an array of maladies, from deadly diseases …
physiology plays a decisive role in as diverse an array of maladies, from deadly diseases …
[HTML][HTML] Peptide-based synthetic vaccines
M Skwarczynski, I Toth - Chemical science, 2016 - pubs.rsc.org
Classically all vaccines were produced using live or attenuated microorganisms or parts of
them. However, the use of whole organisms, their components or the biological process for …
them. However, the use of whole organisms, their components or the biological process for …
Antigens reversibly conjugated to a polymeric glyco-adjuvant induce protective humoral and cellular immunity
Fully effective vaccines for complex infections must elicit a diverse repertoire of antibodies
(humoral immunity) and CD8+ T-cell responses (cellular immunity). Here, we present a …
(humoral immunity) and CD8+ T-cell responses (cellular immunity). Here, we present a …
Multifaceted roles of disulfide bonds. Peptides as therapeutics
M Gongora-Benitez, J Tulla-Puche… - Chemical Reviews, 2014 - ACS Publications
In the last century, small-molecule natural products were the main inspiration for most drug
discovery programs based either on high-throughput screening (HTS) or rational design …
discovery programs based either on high-throughput screening (HTS) or rational design …
[HTML][HTML] Advances in infectious disease vaccine adjuvants
J Fan, S Jin, L Gilmartin, I Toth, WM Hussein… - Vaccines, 2022 - mdpi.com
Vaccines are one of the most significant medical interventions in the fight against infectious
diseases. Since their discovery by Edward Jenner in 1796, vaccines have reduced the …
diseases. Since their discovery by Edward Jenner in 1796, vaccines have reduced the …