Defenses of multidrug resistant pathogens against reactive nitrogen species produced in infected hosts
SM Carvalho, JZ Beas, MAM Videira… - Advances in Microbial …, 2022 - Elsevier
Bacterial pathogens have sophisticated systems that allow them to survive in hosts in which
innate immunity is the frontline of defense. One of the substances produced by infected …
innate immunity is the frontline of defense. One of the substances produced by infected …
Giardia duodenalis: Flavohemoglobin is involved in drug biotransformation and resistance to albendazole
EO Pech-Santiago, R Argüello-García… - PLoS …, 2022 - journals.plos.org
Giardia duodenalis causes giardiasis, a major diarrheal disease in humans worldwide
whose treatment relies mainly on metronidazole (MTZ) and albendazole (ABZ). The …
whose treatment relies mainly on metronidazole (MTZ) and albendazole (ABZ). The …
Ordered Motions in the Nitric-Oxide Dioxygenase Mechanism of Flavohemoglobin and Assorted Globins with Tightly Coupled Reductases
PR Gardner - Protein Reviews: Volume 23, 2022 - Springer
Nitric-oxide dioxygenases (NODs) activate and combine O2 with NO to form nitrate. A variety
of oxygen-binding hemoglobins with associated partner reductases or electron donors …
of oxygen-binding hemoglobins with associated partner reductases or electron donors …
Dioxygen and glucose force motion of the electron-transfer switch in the iron (III) flavohemoglobin-type nitric oxide dioxygenase
AM Gardner, PR Gardner - Journal of Inorganic Biochemistry, 2023 - Elsevier
Kinetic and structural investigations of the flavohemoglobin-type NO dioxygenase have
suggested critical roles for transient Fe (III) O 2 complex formation and O 2-forced …
suggested critical roles for transient Fe (III) O 2 complex formation and O 2-forced …