Recent advances in CAR-T cells therapy for colorectal cancer

X Qin, F Wu, C Chen, Q Li - Frontiers in Immunology, 2022 - frontiersin.org
Colorectal cancer (CRC) is the third most common cancer, with a high mortality rate and a
serious impact on people's life and health. In recent years, adoptive chimeric antigen …

Investigating the crosstalk between chronic stress and immune cells: implications for enhanced cancer therapy

YR Lei, F Liao, YC Tian, YN Wang, F Xia… - Frontiers in …, 2023 - frontiersin.org
Chronic stress has a substantial influence on the tumor microenvironment (TME), leading to
compromised effectiveness of anti-cancer therapies through diverse mechanisms. It disrupts …

Identification of copper metabolism and cuproptosis-related subtypes for predicting prognosis tumor microenvironment and drug candidates in hepatocellular …

X Liu, B Sun, Y Yao, L Lai, X Wang, J Xiong… - Frontiers in …, 2022 - frontiersin.org
Copper (Cu) is an essential element of organisms, which can affect the survival of cells.
However, the role of copper metabolism and cuproptosis on hepatic carcinoma is still …

Psychological distress influences lung cancer: Advances and perspectives on the immune system and immunotherapy

H Gui, X Chen, L Li, L Zhu, Q Jing, Y Nie… - International …, 2023 - Elsevier
Lung cancer has the highest incidence rate and mortality worldwide. Moreover, multiple
factors may cause heterogeneity in the efficacy of immunotherapy for lung cancer, and …

Crosstalk between the nervous system and tumor microenvironment: Functional aspects and potential therapeutic strategies

L Wang, J Ge, H Han, Y Jia, Y Qin - Cancer Letters, 2024 - Elsevier
Recent advancements in understanding the tumor microenvironment (TME) have
highlighted the critical role of the nervous system in cancer progression. This review …

Research progress on the roles of dopamine and dopamine receptors in digestive system diseases

X Lu, Q Liu, Y Deng, J Wu, X Mu, X Yang… - Journal of Cellular …, 2024 - Wiley Online Library
Dopamine (DA) is a neurotransmitter synthesized in the human body that acts on multiple
organs throughout the body, reaching them through the blood circulation. Neurotransmitters …

Ansofaxine hydrochloride inhibits tumor growth and enhances Anti-TNFR2 in murine colon cancer model

Q Jing, Q Wan, Y Nie, J Luo, X Zhang, L Zhu… - Frontiers in …, 2023 - frontiersin.org
Introduction: As psychoneuroimmunology flourishes, there is compelling evidence that
depression suppresses the anti-tumor immune response, promotes the progression of …

Dopaminergic Signalling Enhances IL-2 Production and Strengthens Anti-Tumour Response Exerted by Cytotoxic T Lymphocytes in a Melanoma Mouse Model

O Chovar-Vera, E López, F Gálvez-Cancino, C Prado… - Cells, 2022 - mdpi.com
Dopamine has emerged as an important regulator of immunity. Recent evidence has shown
that signalling through low-affinity dopamine receptors exerts anti-inflammatory effects …

The Diagnostic and Prognostic Value of Neurotransmitter Receptor-Related Genes in Colon Adenocarcinoma

J Hu, Y Wu, X Dong, Y Zeng, Y Wang - Molecular Biotechnology, 2023 - Springer
Colorectal cancer (CRC) is a malignant tumor with high morbidity and mortality in the world.
This study aimed to find receptor-related genes (NRGs) with diagnostic and prognostic value …

Abnormally high expression of D1-like dopamine receptors on lupus CD4+ T cells promotes Tfh cell differentiation

F Wu, Z Xiang, Z He, P Yi, M Yang, H Wu… - Lupus Science & …, 2023 - lupus.bmj.com
Objective SLE is a chronic autoimmune disease that places a great burden on human
society. T follicular helper (Tfh) cells play a critical role in the pathological process of SLE …