Enzyme-Instructed Intracellular Peptide Assemblies

Z Liu, J Guo, Y Qiao, B Xu - Accounts of chemical research, 2023 - ACS Publications
Conspectus Higher-order or supramolecular protein assemblies, usually regulated by
enzymatic reactions, are ubiquitous and essential for cellular functions. This evolutionary …

Self-assembly, bioactivity, and nanomaterials applications of peptide conjugates with bulky aromatic terminal groups

IW Hamley - ACS Applied Bio Materials, 2023 - ACS Publications
The self-assembly and structural and functional properties of peptide conjugates containing
bulky terminal aromatic substituents are reviewed with a particular focus on bioactivity …

Enzyme-instructed peptide assembly favored by preorganization for cancer cell membrane engineering

Y Ding, D Zheng, L Xie, X Zhang, Z Zhang… - Journal of the …, 2023 - ACS Publications
Innovative methods for engineering cancer cell membranes promise to manipulate cell–cell
interactions and boost cell-based cancer therapeutics. Here, we illustrate an in situ …

Covalent Organic Framework‐Based Nanomotor for Multimodal Cancer Photo‐Theranostics

J Feng, SP Yang, YQ Shao, YY Sun… - Advanced …, 2023 - Wiley Online Library
Developing efficient integrated diagnosis and treatment agents based on fuel‐free self‐
movement nanomotors remains challenging in antitumor therapy. In this study, a covalent …

Light-triggered self-assembly of peptide nanoparticles into nanofibers in living cells through molecular conformation changes and H-bond interactions

S Sun, HW Liang, H Wang, Q Zou - ACS nano, 2022 - ACS Publications
Controlled self-assembly has attracted extensive interest in biological and
nanotechnological applications. Enzymatic or biocatalytic triggered self-assembly is widely …

Organelle-Mediated Dissipative Self-Assembly of Peptides in Living Cells

H Wang, Y Song, W Wang, N Chen, B Hu… - Journal of the …, 2023 - ACS Publications
Implementing dissipative assembly in living systems is meaningful for creation of living
materials or even artificial life. However, intracellular dissipative assembly remains scarce …

Therapeutic supramolecular polymers: Designs and applications

H Wang, J Mills, B Sun, H Cui - Progress in Polymer Science, 2023 - Elsevier
The self-assembly of low-molecular-weight building motifs into supramolecular polymers
has unlocked a new realm of materials with distinct properties and tremendous potential for …

[HTML][HTML] Fluorescent probes for targeting the Golgi apparatus: design strategies and applications

S Xu, KC Yan, ZH Xu, Y Wang, TD James - Chemical Society Reviews, 2024 - pubs.rsc.org
The Golgi apparatus is an essential organelle constructed by the stacking of flattened
vesicles, that is widely distributed in eukaryotic cells and is dynamically regulated during cell …

[HTML][HTML] Peptide-based low molecular weight photosensitive supramolecular gelators

B Pramanik, S Ahmed - Gels, 2022 - mdpi.com
Over the last couple of decades, stimuli-responsive supramolecular gels comprising
synthetic short peptides as building blocks have been explored for various biological and …

Peptide‐based supramolecular therapeutics for fighting major diseases

Z Wang, H Luo, H Wang, M Xiao, H Jia… - Advanced Functional …, 2024 - Wiley Online Library
Peptide‐based supramolecular therapeutics (PST) refer to those theranostic nanomedicines
based on peptide or peptide derivatives self‐assembly that are constructed in vitro or in vivo …