New mathematical methods in pharmacokinetic modeling

M ? urišová, L Dedik - Basic & clinical pharmacology & …, 2005 - Wiley Online Library
In recent years, several new methods for the mathematical modeling have gradually
emerged in pharmacokinetics, and the development of pharmacokinetic models based on …

[HTML][HTML] Monitoring coagulation factors during surgery. A systematic review

JE Megías-Vericat, S Bonanad-Boix… - Farmacia …, 2021 - Elsevier
Objective The management of surgeries in patients with hemophilia is complex and requires
adequate clotting factor adjustment to avoid bleeding complications and excessive factor …

A system-approach method for the adjustment of time-varying continuous drug infusion in individual patients: A simulation study

M Ďurišová, L Dedík - Journal of pharmacokinetics and …, 2002 - Springer
The aim of this simulation study was to present a system-approach method for adjustment of
continuous drug infusions at time-varying rates, aimed at achieving and then maintaining …

System-approach methods for modeling and testing similarity of in vitro dissolutions of drug dosage formulations

L Dedı́k, M Ďurišová - Computer methods and programs in biomedicine, 2002 - Elsevier
System-approach based modeling methods are used to model dynamic systems describing
in vitro dissolutions of drug dosage formulations. Employing the models of these systems …

[PDF][PDF] System approach to modeling metabolite formation from parent drug: a working example with methotrexate.

L Dedik, M Durisova - Methods and findings in experimental and …, 2002 - researchgate.net
Parent Drug: A Working Example with Methotrexate Page 1 Methods Find Exp Clin Pharmacol
2002, 24(8): 481-486 Copyright O 2002 Prous Science ccc o 79 oss 2002 System Approach …

[PDF][PDF] Weighting function used for adjustment of multiple-bolus drug dosing.

L Dedik, M Durisova, A Bátorová - Methods and findings in …, 2000 - researchgate.net
Multiple-Bolus Drug Dosing Page 1 Methods Find Exp Clin Pharmacol 2000, 22(7): 543-549
Copyright O 2000 Prous Science CCC: ()3700355/2000 Weighting Function Used for Adjustment …

Modeling behavior of protein C during and after subcutaneous administration

MV Chaubal, L Dedík, M Durisová… - Oxygen Transport to Tissue …, 2005 - Springer
Protein C is an important blood factor protein that regulates the blood coagulation process.
Deficiency of protein C can lead to excessive coagulation that results in lack of tissue …

[PDF][PDF] HOSPITALARIA

JE Megías-Vericat, S Bonanad-Boix… - aulamedica.es
Objective: The management of surgeries in patients with hemophilia is complex and
requires adequate clotting factor adjustment to avoid bleeding complications and excessive …

[引用][C] durisova ADVANCED METHODS FOR MODELING BIOMEDICAL SYSTEMS

M ĎURIŠOVÁ