Extracellular polymeric substances (EPS) constitutes crucial elements within bacterial
biofilms, facilitating accelerated antimicrobial resistance and conferring defense against the …

Microneedles (MNs) are a novel transdermal drug delivery technique that penetrate the skin
stratum corneum and deliver drugs to the target site, which are safer and more effective than …

Biomedical applications of composite hydrogels are attractive because of their
characteristics. Gelatin/poly (vinyl pyrrolidone)(PVP) and HAp nanocomposite hydrogel are …

Dissolvable polymeric microneedles (DPMNs) have emerged as a powerful technology for
the localized treatment of diseases, such as melanoma. Herein, we fabricated a DPMN …

Polymeric hydrogels are a complex class of materials with one common feature—the ability
to form three-dimensional networks capable of imbibing large amounts of water or biological …

Baclofen (BAC) is the first-line recommendation to treat spasticity in people with multiple
sclerosis whose treatment goals include improving mobility or easing pain. The short half-life …

Abstract Cuprous oxide nanoparticles (Cu2ONPs) are low-cost and exhibit unique physical
and antibacterial efficiency against gram-positive and gram-negative bacteria that increase …

Rutin, a flavonoid glycoside phytochemical compound, has a remarkable antiobesity effect.
However, its therapeutic potential is hindered by its poor water solubility and low oral …

Telmisartan (TMN), an angiotensin receptor blocker (ARB) drug, is being considered as an
alternative therapy for Alzheimer's disease (ALZ). However, when taken orally, its low water …

Microneedles are a transdermal drug delivery system in which the needle punctures the
epithelium to deliver the drug directly to deep tissues, thus avoiding the influence of the first …