Myomodulin Increases Ih and Inhibits the Na/K Pump to Modulate Bursting in Leech Heart Interneurons

AE Tobin, RL Calabrese - Journal of neurophysiology, 2005 - journals.physiology.org
In the medicinal leech, a rhythmically active 14-interneuron network composes the central
pattern generator for heartbeat. In two segmental ganglia, bilateral pairs of reciprocally …

The neuroendocrine system of annelids

M Salzet - Canadian journal of zoology, 2001 - cdnsciencepub.com
Chez les vertébrés, le système endocrinien est basé sur l'échange de signaux chimiques
entre les neurones et les structures endocriniennes. Le résultat final peut être obtenu via les …

Amine modulation of the transient potassium current in identified cells of the lobster stomatogastric ganglion

JH Peck, ST Nakanishi, R Yaple… - Journal of …, 2001 - journals.physiology.org
The pyloric network of the stomatogastric ganglion of the lobster Panulirus interruptus is a
model system used to understand how motor networks change their output to produce a …

A slow outward current activated by FMRFamide in heart interneurons of the medicinal leech

F Nadim, RL Calabrese - Journal of Neuroscience, 1997 - Soc Neuroscience
The endogenous neuropeptide FMRFamide (Phe-Met-Arg-Phe-NH2) can accelerate the
oscillation of reciprocally inhibitory pairs of interneurons that pace heartbeat in the medicinal …

Neuromodulation can be simple: myoinhibitory peptide, contained in dedicated regulatory pathways, is the only neurally-mediated peptide modulator of stick insect leg …

S Liessem, D Kowatschew, S Dippel… - Journal of …, 2021 - Soc Neuroscience
In the best studied cases (Aplysia feeding, crustacean stomatogastric system), peptidergic
modulation is mediated by large numbers of peptides. Furthermore, in Aplysia, excitatory …

Synaptic mechanisms in invertebrate pattern generation

EC Cropper, KR Weiss - Current opinion in neurobiology, 1996 - Elsevier
Although individual neurons can be intrinsically oscillatory and can be network pacemakers,
motor patterns are often generated in a more distributed manner. Synaptic connections with …

Modulatory effects of myomodulin on the excitability and membrane currents in Retzius cells of the leech

Y Wang, JA Strong, CL Sahley - Journal of …, 1999 - journals.physiology.org
Ion channel modulation by the peptide myomodulin (MM) has been demonstrated in a wide
variety of organisms including Aplysia, Lymnaea, and Pleurobranchaea. This neural and …

Bursting Dynamics Based on the Persistent Na and Na/K Pump Currents: A Dynamic Clamp Approach

R Erazo-Toscano, M Fomenko, S Core, RL Calabrese… - 2023 - eneuro.org
Life-supporting rhythmic motor functions like heart-beating in invertebrates and breathing in
vertebrates require an indefatigable generation of a robust rhythm by specialized oscillatory …

Glial hyperpolarization upon nerve root stimulation in the leech Hirudo medicinalis

J Schmidt, P Prinz, JW Deitmer - Glia, 1999 - Wiley Online Library
Hyperpolarizing responses in neuropil glial cells evoked by nerve root stimulation were
studied in the central nervous system of the leech Hirudo medicinalis using intracellular …

Bursting Dynamics Based on the Persistent Na+ and Na+/K+ Pump Currents: A Dynamic Clamp Approach

R Erazo-Toscano, M Fomenko, S Core, RL Calabrese… - eneuro, 2023 - eneuro.org
Life-supporting rhythmic motor functions like heart-beating in invertebrates and breathing in
vertebrates require an indefatigable generation of a robust rhythm by specialized oscillatory …