Adiponectin is a secretory protein, primarily produced in adipocytes. However, low but
detectable expression of adiponectin can be observed in cell types beyond adipocytes …

The kidney functions through the coordination of approximately one million multifunctional
nephrons in 3-dimensional space. Molecular understanding of the kidney has relied on …

The glomerulus is a multicellular functional tissue unit (FTU) of the nephron that is
responsible for blood filtration. Each glomerulus contains multiple substructures and cell …

Ferroptosis, a form of regulated necrosis characterized by peroxidation of lipids such as
arachidonic acid‐containing phosphatidylethanolamine (PE), contributes to the …

Lipid imaging mass spectrometry (LIMS) has been tested in several pathological contexts,
demonstrating its ability to segregate and isolate lipid signatures in complex tissues, thanks …

Diabetes is a main risk factor for kidney disease, causing diabetic nephropathy in close to
half of all patients with diabetes. Metabolism has recently been identified to be decisive in …

Lipids are essential cellular components forming membranes, serving as energy reserves,
and acting as chemical messengers. Dysfunction in lipid metabolism and signaling is …

Mass spectrometry imaging (MSI), which quantifies the underlying chemistry with molecular
spatial information in tissue, represents an emerging tool for the functional exploration of …

Highlights•Spatial metabolomics technology has made great advancements in recent
years.•Metabolic molecular histology is a powerful tool to reveal cellular states.•Dynamic …

Probably, the most important factor for the survival of a melanoma patient is early detection
and precise diagnosis. Although in most cases these tasks are readily carried out by …