BACKGROUND: Galectin-3 and soluble ST2 (sST2) are novel serum biomarkers of chronic
heart failure. METHODS AND RESULTS: The biological variability of galectin-3 and sST2 …

It is only a matter of time before the use of high-sensitivity cardiac troponin assays (hs-cTn)
becomes common throughout the United States. In preparation for this inevitability, this …

Background: Cardiac myosin-binding protein C (cMyC) is a cardiac-restricted protein that is
more abundant than cardiac troponins (cTn) and is released more rapidly after acute …

Aims While cardiac troponin measurements have significantly improved the early diagnosis
of myocardial infarction, the timely biomarker-based diagnosis of unstable angina pectoris …

BACKGROUND The early triage of patients toward rule-out and rule-in of acute myocardial
infarction (AMI) is challenging. Therefore, we aimed to develop a 2-h algorithm that uses …

Objective We aimed to prospectively derive and validate a novel 0-/1-hour algorithm using
high-sensitivity cardiac troponin I (hs-cTnI) for the early “rule-out” and “rule-in” of acute …

Cardiac troponins (cTn) are currently the standard of care for the diagnosis of acute coronary
syndromes (ACS) in patients presenting to the emergency department (ED) with chest pain …

Aims: This systematic review aimed to investigate the diagnostic accuracy of combined
cardiac troponin (cTn) and copeptin assessment in comparison to cTn alone for early rule …

Background The associations between highsensitivity troponin I (hsTnI) levels and
coronary artery disease (CAD) severity and progression remain unclear. We investigated …

Aims Several high-sensitivity cardiac troponin (hs-cTn) assays have recently been
developed. It is unknown which hs-cTn provides the most accurate prognostic information …