Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …

Skeletal muscle, which accounts for approximately 40% of total body weight, is one of the
most dynamic and plastic tissues in the human body and plays a vital role in movement …

Although it is well described that mitochondria are at the epicentre of the energy demands of
a cell, it is becoming important to consider how each cell tailors its mitochondrial …

The prevailing notion that reduced cofactors NADH and FADH 2 transfer electrons from the
tricarboxylic acid cycle to the mitochondrial electron transfer system creates ambiguities …

Exercise has long been acknowledged for its powerful disease-preventing, health-promoting
effects. However, the cellular and molecular mechanisms responsible for the beneficial …

Cellular homeostasis is continuously challenged by environmental cues and cellular stress
conditions. In their defense, cells need to mount appropriate stress responses that …

Background: Metabolite-based sensors are attractive and highly valued for monitoring
physiological parameters during rest and/or during physical activities. Owing to their …

Type 2 diabetes mellitus accounts for about 90% of cases of diabetes and is considered one
of the most important problems of our time. Despite a significant number of studies on …

Mechanotransduction is a strictly regulated process whereby mechanical stimuli, including
mechanical forces and properties, are sensed and translated into biochemical signals …

The sleep-breathing condition obstructive sleep apnea (OSA) is characterized by repetitive
upper airway collapse, which can exacerbate oxidative stress and free radical generation …