Objective: To investigate the prevalence and determinants of virologic failure and acquired
drug resistance-associated mutations (DRMs) in HIV-infected children and adolescents in …

Introduction Antiretroviral treatment (ART) has been scaled up over the last decade but
compared to adults, children living with HIV are less likely to receive ART. Moreover …

Objective: To determine the long-term outcomes of treatment and prevalence of genotypic
drug resistance in children and adolescents on combination antiretroviral therapy. Methods …

We sought to determine the pattern of resistance-associated mutations (RAMs) among HIV-1-
infected children failing first-line antiretroviral therapy (ART) and ascertain their response to …

Abstract Background In Tanzania, HIV-1 RNA testing is rarely available and not standard of
care. Determining virologic failure is challenging and resistance mutations accumulate …

A large cohort of 220 HIV-1-infected children (median [range] age: 12 [4–17] years) was
cared and followed up in the Central African Republic, including 198 in 1st-line and 22 in …

Objectives: The objectives of this study were to determine HIV drug resistance (HIVDR)
prevalence in Zambian infants upon diagnosis, and to determine how changing prevention …

Promotion of the low risk “ABC” behaviors—Abstinence, Being faithful, and Condom use—
has had only limited success in Africa. This book draws on a large qualitative study affiliated …

Objectives In resource-limited settings, it is a challenge to get quality clinical specimens due
to poor infrastructure for their collection, transportation, processing and storage. Using dried …

Abstract Between 2007 and 2008, the Mozambique Ministry of Health conducted an
assessment of human immunodeficiency virus drug resistance (HIVDR) using World Health …