The modern epidemic of syphilis

KG Ghanem, S Ram, PA Rice - New England Journal of Medicine, 2020 - Mass Medical Soc
Syphilis Over the past two decades, the incidence of syphilis has increased sharply. The
courses of both untreated and treated disease can be unpredictable. This review presents …

[PDF][PDF] 2020 European guideline on the management of syphilis.

M Janier, M Unemo, N Dupin, GS Tiplica… - Journal of the European …, 2021 - cnr-ist.fr
2020 European guideline on the management of syphilis Page 1 GUIDELINES 2020 European
guideline on the management of syphilis M. Janier,1,* M. Unemo,2 N. Dupin,3 GS Tiplica,4 M …

[HTML][HTML] Congenital syphilis in the twenty-first century: an area-based study

S Salomè, MD Cambriglia, SM Scarano… - European journal of …, 2023 - Springer
The resurgence of syphilis and subsequent risk for newborns has been described
worldwide; however, European data on this congenital infection is lacking. We report the …

[HTML][HTML] Global, regional, and national trends of syphilis from 1990 to 2019: the 2019 global burden of disease study

YT Tao, TY Gao, HY Li, YT Ma, HJ Li, CY Xian-Yu… - BMC Public Health, 2023 - Springer
Background Syphilis is a sexually transmitted disease caused by Treponema pallidum, and
the infection source is syphilis patients. This study aimed to estimate the incidence, mortality …

[HTML][HTML] Ancient bacterial genomes reveal a high diversity of Treponema pallidum strains in early modern Europe

K Majander, S Pfrengle, A Kocher, J Neukamm… - Current Biology, 2020 - cell.com
Syphilis is a globally re-emerging disease, which has marked European history with a
devastating epidemic at the end of the 15 th century. Together with non-venereal treponemal …

Treponema pallidum detection in lesion and non-lesion sites in men who have sex with men with early syphilis: a prospective, cross-sectional study

JM Towns, DE Leslie, I Denham, R Wigan… - The Lancet Infectious …, 2021 - thelancet.com
Background Syphilis transmission is increasing, and precisely how Treponema pallidum is
transmitted sexually from person to person is unclear. We aimed to determine the frequency …

[HTML][HTML] Clinical protocols and treatment guidelines for the management of maternal and congenital syphilis in brazil and portugal: analysis and comparisons: a …

TK de Brito Pinto, ACGDP da Cunha-Oliveira… - International Journal of …, 2022 - mdpi.com
(1) Background: Maternal syphilis (MS) and congenital syphilis (CS) are serious public
health problems worldwide due to their high morbidity and mortality rates.(2) Objective …

[HTML][HTML] Point-of-care diagnostics for diagnosis of active syphilis infection: needs, challenges and the way forward

MD Pham, JJ Ong, DA Anderson, HE Drummer… - International Journal of …, 2022 - mdpi.com
Syphilis, a curable sexually transmitted infection, has re-emerged as a global public health
threat with an estimated 5.6 million new cases every year. Pregnant women and men who …

[HTML][HTML] Diagnostic tools for neurosyphilis: a systematic review

GHP Boog, JVZ Lopes, JV Mahler, M Solti… - BMC Infectious …, 2021 - Springer
Purpose Increasing incidences of syphilis highlight the preoccupation with the occurrence of
neurosyphilis. This study aimed to understand the current diagnostic tools and their …

[PDF][PDF] Syphilis: a mini review of the history, epidemiology and focus on microbiota

EM Santo Raffaele Mercuri, A Cerullo… - New …, 2022 - newmicrobiologica.org
The origin of syphilis has been controversial and there are many theories that try to explain
it. One of them is the “Columbian Hypothesis”, which claims that syphilis was brought from …