The results of many studies in a variety of species have significantly advanced our
understanding of the role of visual experience and the mechanisms of postnatal eye growth …

Glucagon-like peptide 1 (GLP-1) is a 30-amino acid peptide hormone produced in the
intestinal epithelial endocrine L-cells by differential processing of proglucagon, the gene …

OBJECTIVE Delayed-release metformin (Met DR) is formulated to deliver the drug to the
lower bowel to leverage the gut-based mechanisms of metformin action with lower plasma …

Incretins are gut hormones that are secreted from enteroendocrine cells into the blood within
minutes after eating. One of their many physiological roles is to regulate the amount of …

Stressors elicit a complex but variable suite of endocrine events. Comparative studies of the
stress response have focused primarily on the adrenocortical response to stress, in …

One of the symptoms of diabetes is the progressive development of neuropathies. One
mechanism to replace neurons in the CNS is through the activation of stem cells and …

Proglucagon is cleaved to glucagon by prohormone convertase 2 (PC2) in pancreatic a-
cells, but is cleaved to glucagon-like peptide-1 (GLP-1) by PC1 in intestinal L-cells. The aim …

Glucagon-like peptide-1 (GLP-1) is released in response to meals and exerts important roles
in the maintenance of normal glucose homeostasis. GLP-1 is also important in the regulation …

Emerging evidence has suggested a possible physiologic role for peripheral glucagon-like
peptide 1 (GLP-1) in regulating glucose metabolism and food intake. The likely site of action …

It has been suggested that hormones released after nutrient absorption, such as glucose-
dependent insulinotropic peptide (GIP) and glucagon-like peptide 2 (GLP-2), could be …