Psoriasis is a chronic, immune-mediated, inflammatory disease that is pathogenically driven
by proinflammatory cytokines. This article reviews the immunologic role of interleukin (IL)-17 …

Psoriasis is a multisystemic, inflammatory skin condition that can affect many areas of the
body, but most commonly the extensor surfaces of the elbows and knees, and sometimes …

Background Tofacitinib is an oral Janus kinase inhibitor that is under investigation for the
treatment of psoriatic arthritis. We evaluated tofacitinib in patients with active psoriatic …

Background Tofacitinib is an oral Janus kinase inhibitor that is under investigation for the
treatment of psoriatic arthritis. We evaluated tofacitinib in patients with active psoriatic …

Objective To assess the safety and efficacy of ixekizumab, a monoclonal antibody that
inhibits interleukin-17A, in a double-blind phase III trial enrolling patients with active …

AIM To investigate whether immune mediated diseases (IMD) are more frequent in patients
with inflammatory bowel disease (IBD). METHODS In this population based registry study, a …

Objective To characterize psoriatic arthritis (PsA) patients with dactylitis or enthesitis and
evaluate the associations of these manifestations with disease activity and patient‐reported …

Nowadays, more than 80 autoimmune disorders are recognized, in which an aberrant
immune response against different organs and tissues plays a crucial role. Hormonal …

The complex crosstalk between the immune and the skeletal systems plays an
indispensable role in the maintenance of skeletal homeostasis. Various cytokines are …

Psoriatic arthritis (PsA) is a heterogeneous and inflammatory disease with diverse clinical
manifestations, including psoriasis, nail psoriasis, peripheral joint disease, axial joint …