Clostridium difficile infection

J Czepiel, M Dróżdż, H Pituch, EJ Kuijper… - European Journal of …, 2019 - Springer
Clostridium difficile (C. difficile) is a Gram-positive, spore-forming, anaerobic bacillus, which
is widely distributed in the intestinal tract of humans and animals and in the environment. In …

Clostridium difficile infection

WK Smits, D Lyras, DB Lacy, MH Wilcox… - Nature reviews Disease …, 2016 - nature.com
Infection of the colon with the Gram-positive bacterium Clostridium difficile is potentially life
threatening, especially in elderly people and in patients who have dysbiosis of the gut …

Public health risk of antimicrobial resistance transfer from companion animals

C Pomba, M Rantala, C Greko… - Journal of …, 2017 - academic.oup.com
Antimicrobials are important tools for the therapy of infectious bacterial diseases in
companion animals. Loss of efficacy of antimicrobial substances can seriously compromise …

[HTML][HTML] Clostridium difficile infection: epidemiology, diagnosis and understanding transmission

JSH Martin, TM Monaghan, MH Wilcox - … reviews Gastroenterology & …, 2016 - nature.com
Clostridium difficile infection (CDI) continues to affect patients in hospitals and communities
worldwide. The spectrum of clinical disease ranges from mild diarrhoea to toxic megacolon …

Diverse Sources of C. difficile Infection Identified on Whole-Genome Sequencing

DW Eyre, ML Cule, DJ Wilson, D Griffiths… - … England Journal of …, 2013 - Mass Medical Soc
Background It has been thought that Clostridium difficile infection is transmitted
predominantly within health care settings. However, endemic spread has hampered …

Clostridium difficile binary toxin CDT: Mechanism, epidemiology, and potential clinical importance

DN Gerding, S Johnson, M Rupnik, K Aktories - Gut microbes, 2014 - Taylor & Francis
Binary toxin (CDT) is frequently observed in Clostridium difficile strains associated with
increased severity of C. difficile infection (CDI). CDT belongs to the family of binary ADP …

Insect-based diet, a promising nutritional source, modulates gut microbiota composition and SCFAs production in laying hens

L Borrelli, L Coretti, L Dipineto, F Bovera, F Menna… - Scientific reports, 2017 - nature.com
Insects could be potential nutritional sources both for humans and animals. Among these,
Hermetia illucens, with good amount of chitin and proteins, represents a suitable diet …

Diversity and evolution in the genome of Clostridium difficile

DR Knight, B Elliott, BJ Chang… - Clinical microbiology …, 2015 - Am Soc Microbiol
Clostridium difficile infection (CDI) is the leading cause of antimicrobial and health care-
associated diarrhea in humans, presenting a significant burden to global health care …

The livestock reservoir for antimicrobial resistance: a personal view on changing patterns of risks, effects of interventions and the way forward

FM Aarestrup - … Transactions of the Royal Society B …, 2015 - royalsocietypublishing.org
The purpose of this review was to provide an updated overview on the use of antimicrobial
agents in livestock, the associated problems for humans and current knowledge on the …

Wastewater treatment plants, an “escape gate” for ESCAPE pathogens

LG Marutescu, M Popa, I Gheorghe-Barbu… - Frontiers in …, 2023 - frontiersin.org
Antibiotics are an essential tool of modern medicine, contributing to significantly decreasing
mortality and morbidity rates from infectious diseases. However, persistent misuse of these …