Extracellular regulation of VEGF: isoforms, proteolysis, and vascular patterning
P Vempati, AS Popel, F Mac Gabhann - Cytokine & growth factor reviews, 2014 - Elsevier
The regulation of vascular endothelial growth factor A (VEGF) is critical to
neovascularization in numerous tissues under physiological and pathological conditions …
neovascularization in numerous tissues under physiological and pathological conditions …
A systems biology view of blood vessel growth and remodelling
Blood travels throughout the body in an extensive network of vessels–arteries, veins and
capillaries. This vascular network is not static, but instead dynamically remodels in response …
capillaries. This vascular network is not static, but instead dynamically remodels in response …
Simulating tissue mechanics with agent-based models: concepts, perspectives and some novel results
P Van Liedekerke, MM Palm, N Jagiella… - Computational particle …, 2015 - Springer
In this paper we present an overview of agent-based models that are used to simulate
mechanical and physiological phenomena in cells and tissues, and we discuss underlying …
mechanical and physiological phenomena in cells and tissues, and we discuss underlying …
Nonlinear modelling of cancer: bridging the gap between cells and tumours
Despite major scientific, medical and technological advances over the last few decades, a
cure for cancer remains elusive. The disease initiation is complex, and including initiation …
cure for cancer remains elusive. The disease initiation is complex, and including initiation …
[图书][B] Multiscale modeling of cancer: an integrated experimental and mathematical modeling approach
V Cristini, J Lowengrub - 2010 - books.google.com
Mathematical modeling, analysis and simulation are set to play crucial roles in explaining
tumor behavior, and the uncontrolled growth of cancer cells over multiple time and spatial …
tumor behavior, and the uncontrolled growth of cancer cells over multiple time and spatial …
Effects of endothelial cell proliferation and migration rates in a computational model of sprouting angiogenesis
Angiogenesis, the recruitment of new blood vessels, is a critical process for the growth,
expansion, and metastatic dissemination of developing tumors. Three types of cells make up …
expansion, and metastatic dissemination of developing tumors. Three types of cells make up …
A review of mathematical models for the formation of vascular networks
M Scianna, CG Bell, L Preziosi - Journal of theoretical biology, 2013 - Elsevier
Two major mechanisms are involved in the formation of blood vasculature: vasculogenesis
and angiogenesis. The former term describes the formation of a capillary-like network from …
and angiogenesis. The former term describes the formation of a capillary-like network from …
The application of pulsed electromagnetic fields (PEMFs) for bone fracture repair: past and perspective findings
Bone fractures are one of the most commonly occurring injuries of the musculoskeletal
system. A highly complex physiological process, fracture healing has been studied …
system. A highly complex physiological process, fracture healing has been studied …
Spatiotemporal multi-scale modeling of radiopharmaceutical distributions in vascularized solid tumors
We present comprehensive mathematical modeling of radiopharmaceutical spatiotemporal
distributions within vascularized solid tumors. The novelty of the presented model is at …
distributions within vascularized solid tumors. The novelty of the presented model is at …
The fluid mechanics of cancer and its therapy
P Koumoutsakos, I Pivkin, F Milde - Annual review of fluid …, 2013 - annualreviews.org
Fluid mechanics is involved in the growth, progression, metastasis, and therapy of cancer.
Blood vessels transport oxygen and nutrients to cancerous tissues, provide a route for …
Blood vessels transport oxygen and nutrients to cancerous tissues, provide a route for …