Chronic infection with viral hepatitis affects half a billion individuals worldwide and can lead
to cirrhosis, cancer, and liver failure. Liver cancer is the third leading cause of cancer …

Recent advances in systemic and locoregional treatments for patients with unresectable or
advanced hepatocellular carcinoma (HCC) have resulted in improved response rates. This …

A potentially curative hepatic resection is the optimal treatment for hepatocellular carcinoma
(HCC), but most patients are not candidates for resection and most resected HCCs …

Liver cancer is a common cancer worldwide. Although the etiological factors of liver
carcinogenesis are well defined, the underlying molecular mechanisms remain largely …

Malignant liver tumours include a wide range of primary and secondary tumours. Although
surgery remains the mainstay of curative treatment, modern therapies integrate a variety of …

Background Hepatocellular carcinoma (HCC) is one of the most common malignant tumors,
and many patients are diagnosed with advanced disease. The treatment of advanced liver …

Background Hepatocellular carcinoma (HCC) is one of the most common malignancies
globally. Despite aggressive and multimodal treatment regimens, the overall survival of HCC …

Importance For more than a decade, sorafenib has been the only systemic treatment option
for patients with advanced hepatocellular carcinoma (HCC). However, rapid progress over …

Inflammation in the tumor microenvironment is a hallmark of cancer and is recognized as a
key characteristic of carcinogens. However, the failure of resolution of inflammation in …

Circular RNAs (circRNAs) have confirmed to participate in diverse biological functions in
cancer. However, the expression patterns of circRNAs on hepatocellular carcinoma (HCC) …