The role of exosomal PD-L1 in tumor progression and immunotherapy
F Xie, M Xu, J Lu, L Mao, S Wang - Molecular cancer, 2019 - Springer
Programmed death ligand 1 (PD-L1), a type I transmembrane protein, binds to its receptor
PD-1 to suppress the activation of T cells, thereby maintaining immunological homeostasis …
PD-1 to suppress the activation of T cells, thereby maintaining immunological homeostasis …
Exosomes from mesenchymal stem/stromal cells: a new therapeutic paradigm
K Yin, S Wang, RC Zhao - Biomarker research, 2019 - Springer
Mesenchymal stem/stromal cells (MSCs) have been demonstrated to hold great potential for
the treatment of several diseases. Their therapeutic effects are largely mediated by …
the treatment of several diseases. Their therapeutic effects are largely mediated by …
[HTML][HTML] The biology, function, and applications of exosomes in cancer
J Liu, L Ren, S Li, W Li, X Zheng, Y Yang, W Fu… - … Pharmaceutica Sinica B, 2021 - Elsevier
Exosomes are cell-derived nanovesicles with diameters from 30 to 150 nm, released upon
fusion of multivesicular bodies with the cell surface. They can transport nucleic acids …
fusion of multivesicular bodies with the cell surface. They can transport nucleic acids …
The functions and clinical application potential of exosomes derived from adipose mesenchymal stem cells: a comprehensive review
P Hong, H Yang, Y Wu, K Li, Z Tang - Stem cell research & therapy, 2019 - Springer
Exosomes are extracellular membranous nanovesicles that mediate local and systemic
intercellular communication by transporting proteins or nucleic acids (DNA and RNA) into …
intercellular communication by transporting proteins or nucleic acids (DNA and RNA) into …
New insight into isolation, identification techniques and medical applications of exosomes
XX Yang, C Sun, L Wang, XL Guo - Journal of controlled release, 2019 - Elsevier
Exosomes, which are nano-vesicles produced by most cell types, play an irreplaceable role
in cell-cell communication. They are extracellular small vesicles that can delivery various …
in cell-cell communication. They are extracellular small vesicles that can delivery various …
IL-6 and IL-8 secreted by tumour cells impair the function of NK cells via the STAT3 pathway in oesophageal squamous cell carcinoma
Background Recurrence and metastasis are the leading causes of tumour-related death in
patients with oesophageal squamous cell carcinoma (ESCC). Tumour-infiltrating natural …
patients with oesophageal squamous cell carcinoma (ESCC). Tumour-infiltrating natural …
Cancer-derived exosomal TRIM59 regulates macrophage NLRP3 inflammasome activation to promote lung cancer progression
M Liang, X Chen, L Wang, L Qin, H Wang… - Journal of Experimental …, 2020 - Springer
Background Exosomes are emerging as important mediators of the cross-talk between
tumor cells and the microenvironment. The communication between tumor-derived …
tumor cells and the microenvironment. The communication between tumor-derived …
The roles of small extracellular vesicles in cancer and immune regulation and translational potential in cancer therapy
Extracellular vesicles (EVs) facilitate the extracellular transfer of proteins, lipids, and nucleic
acids and mediate intercellular communication among multiple cells in the tumour …
acids and mediate intercellular communication among multiple cells in the tumour …
[HTML][HTML] Small extracellular vesicles: non-negligible vesicles in tumor progression, diagnosis, and therapy
X Zhou, Y Jia, C Mao, S Liu - Cancer Letters, 2023 - Elsevier
Small extracellular vesicles (sEVs) such as exosomes are nanoscale membranous particles
(< 200 nm) that have emerged as crucial targets for liquid biopsy and as promising drug …
(< 200 nm) that have emerged as crucial targets for liquid biopsy and as promising drug …
Exosomes from different cells: Characteristics, modifications, and therapeutic applications
M Li, S Li, C Du, Y Zhang, Y Li, L Chu, X Han… - European Journal of …, 2020 - Elsevier
Exosomes are cystic vesicles secreted by living cells with a phospholipid bilayer membrane.
Importantly, these vesicles could serve to carry lipids, proteins, genetic materials, and …
Importantly, these vesicles could serve to carry lipids, proteins, genetic materials, and …