Pterostilbene (PTS), a compound most abundantly found in blueberries, is a natural analog
of resveratrol. Several plant species, such as peanuts and grapes, produce PTS. While …

Active pharmaceutical ingredients (APIs) extracted and isolated from traditional Chinese
medicines (TCMs) are of interest for drug development due to their wide range of biological …

Gallic acid (GA) is a naturally occurring polyphenolic compound exhibiting anti-tumor
activity. To clarify the capability of GA in optimizing the in vitro/in vivo properties of the first …

The most favored approach for drug administration is the oral route. Several anticancer
drugs come under this category and mostly lack solubility and oral bioavailability, which are …

The aim of our research was to improve the solubility and antioxidant activity of pterostilbene
(PTR) by developing a novel amorphous solid dispersion (ASD) with Soluplus®(SOL). DSC …

Co-crystallization is a promising approach for improving physical and pharmacological
properties of API, viz., solubility, dissolution rate, stability, hygroscopicity, tablet ability …

In this study, amorphous solid dispersions (ASDs) of pterostilbene (PTR) with
polyvinylpyrrolidone polymers (PVP K30 and VA64) were prepared through milling, affirming …

Etoricoxib (ETR) is a non-ionizable BCS class II drug with no typical hydrogen bond donors
and low solubility in water. Cocrystal was proved to be a good strategy to improve …

Background: Scientists, academicians, and researchers from academics and the
pharmaceutical industries have all expressed interest in the design and production of …

methylnicotinamide was utilized to create co-crystal/salts for the first time. By introducing it
into the co-crystallization system based on different carboxylic acids of mono-to dicarboxylic …