Background The estimated worldwide incidence of perioperative or periprocedural
anaphylaxis (PA) is between 1 in 1250 and 1 in 20,000 procedures. Objective To evaluate …

Refractory anaphylaxis (unresponsive to treatment with at least two doses of minimum 300
μg adrenaline) is a rare and often fatal hypersensitivity reaction. Comprehensive data on its …

Background There is no accepted grading system classifying the severity of immediate
reactions to drugs. Objective The purpose of this article is to present a proposed grading …

Background Evidence-based guidelines are needed in the United States to improve
evaluation of perioperative allergic reactions including recommendations for subsequent …

Background Details of the current UK drug and allergen exposure were needed for
interpretation of reports of perioperative anaphylaxis to the 6th National Audit Project …

Perioperative anaphylaxis is associated with significant morbidity and mortality. Prompt and
appropriate treatment is required for optimal outcome. Despite general knowledge of this …

Background: Sugammadex is a modified cyclodextrin that is being increasingly used in
anesthetic practice worldwide for the reversal of the aminosteroid neuromuscular blockers …

Simulation-based education is often highlighted as a method to prepare health personnel to
handle clinical emergencies through repeated training and the design of supports. As one of …

Asthma remains a common comorbid condition in patients presenting for anesthetic care. As
a chronic inflammatory disease of the airway, asthma is known to increase the risk of …

Purpose Perioperative anaphylaxis (POA) is an acute severe systemic hypersensitivity
reaction characterized by life-threatening respiratory and circulatory collapse. In our …