Myotonic dystrophy is the most common type of muscular dystrophy in adults and is
characterised by progressive myopathy, myotonia, and multiorgan involvement. Two …

Myotonic dystrophy (DM) is the most common adult muscular dystrophy, characterized by
autosomal dominant progressive myopathy, myotonia and multiorgan involvement. To date …

Myotonic dystrophy type 1 (DM1) and type 2 (DM2) represent the most frequent
multisystemic muscular dystrophies in adulthood. They are progressive, autosomal …

The muscular dystrophies are a group of inherited diseases affecting skeletal muscle that
also affect cardiac muscle. Cardiac involvement occurs as a degenerative process with …

The onset and symptoms of the myotonic dystrophies are diverse, complicating their
diagnoses and limiting a comprehensive approach to their clinical care. This report analyzes …

Myotonic dystrophy type 1 and type 2 (DM1, DM2) are caused by expansions of CTG and
CCTG repeats, respectively. RNAs containing expanded CUG or CCUG repeats interfere …

The myotonic dystrophies are the commonest cause of adult-onset muscular dystrophy.
Phenotypes of DM1 and DM2 are similar, but there are some important differences …

Myotonic Dystrophy Type-2 (DM2) is an autosomal dominant disease caused by the
expansion of a CCTG tetraplet repeat. It is a multisystemic disorder, affecting skeletal …

Myotonic dystrophy is classified as one of the myotonic syndromes although myotonia is
only a minor characteristic of it. It is, in fact, also a multisystem disease with cardiac …

The myotonic disorders are a heterogeneous group of genetically determined diseases that
are unified by the presence of myotonia, which is defined as failure of muscle relaxation after …