Recent advance in the development of the fluorescent responsive probes for the study of ferroptosis

B Dong, S Li, Y Wang, X Tang, R Wang, X Kong… - TrAC Trends in …, 2023 - Elsevier
Ferroptosis is an iron-dependent cell death form with the characteristic of the excessive
accumulation of lipid peroxidation. In recent ten years, a host of researches suggested that …

Factors important in the use of fluorescent or luminescent probes and other chemical reagents to measure oxidative and radical stress

P Wardman - Biomolecules, 2023 - mdpi.com
Numerous chemical probes have been used to measure or image oxidative, nitrosative and
related stress induced by free radicals in biology and biochemistry. In many instances, the …

Reversible Dual Fluorescence-Lifetime Imaging of Mitochondrial GSH and Microviscosity: Real-Time Evaluation of Ferroptosis Status

SY Wang, YC Qu, N Shao, LY Niu… - Analytical Chemistry, 2024 - ACS Publications
Ferroptosis, as a new form of regulated cell death, is implicated in various physiological and
pathological processes. Developing a single probe for an independent analysis of multiple …

A lipid droplets-targetable fluorescent probe for polarity detection in cells of iron death, inflammation and fatty liver tissue

X Tian, D Wu, W Wei, G Dai, Z Li, B Wang… - Chinese Chemical Letters, 2024 - Elsevier
Abnormal accumulation and metabolism of lipid droplets can lead to a variety of diseases.
Polarity, a key parameter of the microenvironment, is closely associated with many diseases …

Recent advances in melittin-based nanoparticles for antitumor treatment: from mechanisms to targeted delivery strategies

X Yu, S Jia, S Yu, Y Chen, C Zhang, H Chen… - Journal of …, 2023 - Springer
As a naturally occurring cytolytic peptide, melittin (MLT) not only exhibits a potent direct
tumor cell-killing effect but also possesses various immunomodulatory functions. MLT shows …

Exploration of Novel Meso-C═N-BODIPY-Based AIE Fluorescent Rotors with Large Stokes Shifts for Organelle-Viscosity Imaging

QH Wan, G Anwar, YX Tang, WJ Shi, XS Chen… - Analytical …, 2024 - ACS Publications
The research on fluorescent rotors for viscosity has attracted extensive interest to better
comprehend the close relationships of microviscosity variations with related diseases …

Fluorescent probes based on bioorthogonal reactions: Construction strategies and applications

H Zhao, Y He, Y Lo, H Song, J Lu - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
The emergence of bioorthogonal reactions has provided numerous opportunities for the
design and fabrication of innovative fluorescence systems, particularly in the analytical field …

A triple-targeting fluorescent probe reveals the glutathione and viscosity crosstalk in mitochondria, endoplasmic reticulum, and nucleoli in cells during ferroptosis

LL Wang, Q Xu, YZ Xie, YR Zhang, MH Zheng… - Sensors and Actuators B …, 2024 - Elsevier
Ferroptosis, a recently termed cell death form, is featured by iron accumulation and lipid
peroxidation, which plays various roles in physiological and pathological processes such as …

Unraveling ferroptosis mechanisms: Tracking Cellular viscosity with small molecular fluorescent probes

N Pareek, S Mendiratta, N Kalita… - Chemistry–An Asian …, 2024 - Wiley Online Library
Ferroptosis is a recently identified form of regulated cell death characterized by iron
accumulation and lipid peroxidation. Numerous functions for ferroptosis have been identified …

A dual-responsive crimson fluorescent probe for real-time diagnosis of alcoholic acute liver injury

S Wang, X Zhao, M Liu, L Yang, M Yu, Z Li - Biosensors and Bioelectronics, 2023 - Elsevier
The polarity and viscosity of the microenvironment are associated with the control of the
onset and progression of pathological diseases, including inflammation, immuno …