Golgi apparatus-targeting fluorescent probe for the imaging of superoxide anion (O2•−) in living cells during ferroptosis

J Chang, Y Wang, X Kong, B Dong, T Yue - Analytica Chimica Acta, 2024 - Elsevier
Ferroptosis is an emerging iron-dependent oxidative cell death type, and recently has been
demonstrated to show close relation with Golgi apparatus (GA). Exploring the fluctuation of …

Visualization of Acrolein Upregulation during Ferroptosis by a Ratiometric Fluorescent Probe

Q Duan, Y Wang, X Zhang, J Han, J Yu, J Jing… - Analytical …, 2024 - ACS Publications
Ferroptosis is a pattern of cell death caused by iron-dependent accumulation of lipid
peroxides and is closely associated with the occurrence and development of multiple …

NIR Fluorescent/Photoacoustic Bimodal Imaging of Ferroptosis in Pancreatic Cancer Using Biothiols-Activable Probes

L Li, Z Zhang, L Zhou, H Ge, Y Zhao, Y Gong… - Analytical …, 2024 - ACS Publications
Ferroptosis modulation is a powerful therapeutic option for pancreatic ductal
adenocarcinoma (PDAC) with a low 5-year survival rate and lack of effective treatment …

Catalytic hairpin assembly-assisted dual-signal amplification platform for ultrasensitive detection of tumor markers and intelligent diagnosis of gastric cancer

R Gao, R Ji, W Dong - Talanta, 2023 - Elsevier
Quantification of extracellular tumor markers has shown great promise for non-invasive
cancer diagnosis. Combined detection of multiple tumor markers instead of a single one is …

Application of the VSP near-infrared fluorescence probe in hyperlipidemia viscosity monitoring

L Yang, C Jin, N Fang, HL Zhu, Z Li - Materials Today Chemistry, 2023 - Elsevier
This study introduces a novel near-infrared fluorescent probe named VSP, designed to
effectively and sensitively monitor viscosity changes both internally and externally. Through …

Ratiometric Fluorescent Probe for Super-Resolution Imaging of Lysosome HClO in Ferroptosis Cells

H Zheng, W Peng, M Liu, S Zhang, X Song… - Analytical …, 2024 - ACS Publications
Ferroptosis is an iron-dependent programmed cell death that is characterized by the
dysregulation of lipid reactive oxygen species (ROS) production, causing abnormal changes …

Unraveling the dual sensing mechanism of hydrogen peroxide probe: Photoinduced electron transfer and unusual local excited state intramolecular proton transfer

H Xu, A Huang, W Hao, Z Xia, D Wu, P Xie, Y Lan… - Journal of …, 2024 - Elsevier
An understanding of hydrogen peroxide's (H 2 O 2) sensing process is crucial for the
development of effective fluorescent probes. In this investigation, we unraveled the sensing …

[HTML][HTML] Visulization of peroxynitrite variation for accurate diagnosis and assessing treatment response of hepatic fibrosis using a Golgi-targetable ratiometric …

T Zhang, Z Li, M Qin, J Zhang, Y Sun, C Liu - Journal of Photochemistry and …, 2024 - Elsevier
Hepatic fibrosis (HF) is caused by persistent inflammation, which is closely associated with
hepatic oxidative stress. Peroxynitrite (ONOO−) is significantly elevated in HF, which would …

A COX2-targeting cancer-specific fluorescent probe for hydrogen sulfide detection in living cells, Caenorhabditis elegans, and zebrafish

F Yuan, Q Zhao, Y Zeng, XF Liao, J Li, B Liu, JF Kou… - Analyst, 2024 - pubs.rsc.org
A novel cyclooxygenase-2 (COX-2) targeted H2S-activated cancer-specific fluorescent
probe, namely, COX2-H2S, was designed and synthesized, with naphthalimide as the …

Dissecting lysosomal viscosity fluctuations in live cells and liver tissues with an ingenious NIR fluorescent probe

Y Zhang, Q Jiang, K Wang, Y Fang, P Zhang, L Wei… - Talanta, 2024 - Elsevier
Viscosity is a pivotal component in the cell microenvironment, while lysosomal viscosity
fluctuation is associated with various human diseases, such as tumors and liver diseases …