[HTML][HTML] Non-alcoholic fatty liver disease: An expanded review

M Benedict, X Zhang - World journal of hepatology, 2017 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) encompasses the simple steatosis to more
progressive steatosis with associated hepatitis, fibrosis, cirrhosis, and in some cases …

[HTML][HTML] Race and ethnicity in non-alcoholic fatty liver disease (NAFLD): a narrative review

K Riazi, MG Swain, SE Congly, GG Kaplan… - Nutrients, 2022 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is a significant public health concern worldwide
with a complex etiology attributed to behavioural, environmental, and genetic causes. The …

Alcoholic liver disease in asia, europe, and north America

S Liangpunsakul, P Haber, GW McCaughan - Gastroenterology, 2016 - Elsevier
Alcoholic liver diseases comprise a spectrum of clinical disorders and changes in liver tissue
that can be detected by pathology analysis. These range from steatosis to more severe signs …

Additive effects of PNPLA3 and TM6SF2 on the histological severity of non‐alcoholic fatty liver disease

BK Koo, SK Joo, D Kim, JM Bae, JH Park… - Journal of …, 2018 - Wiley Online Library
Abstract Background and Aim We investigated the effects of PNPLA3 rs738409, TM6SF2
rs58542926, and MBOAT7‐TMC4 rs641738 variants on metabolic phenotypes and their …

[HTML][HTML] PNPLA3—a potential therapeutic target for personalized treatment of chronic liver disease

XC Dong - Frontiers in medicine, 2019 - frontiersin.org
Patatin-like phospholipase domain-containing protein 3 (PNPLA3) is a lipid droplet-
associated protein that has been shown to have hydrolase activity toward triglycerides and …

[HTML][HTML] The Impact of PNPLA3 rs738409 Genetic Polymorphism and Weight Gain ≥10 kg after Age 20 on Non-Alcoholic Fatty Liver Disease in Non-Obese …

K Nishioji, N Mochizuki, M Kobayashi, M Kamaguchi… - PLoS …, 2015 - journals.plos.org
Non-alcoholic fatty liver disease (NAFLD) in non-obese individuals is inadequately
elucidated. We aim to investigate the impact of known genetic polymorphisms on NAFLD …

[HTML][HTML] Influence of the PNPLA3 rs738409 Polymorphism on Non-Alcoholic Fatty Liver Disease and Renal Function among Normal Weight Subjects

K Oniki, J Saruwatari, T Izuka, A Kajiwara, K Morita… - PloS one, 2015 - journals.plos.org
In normal weight subjects (body mass index< 25 kg/m2), non-alcoholic fatty liver disease
(NAFLD) is likely to coexist with metabolic diseases. The patatin-like phospholipase 3 …

Development of hepatocellular carcinoma in Japanese patients with biopsy‐proven non‐alcoholic fatty liver disease: association between PNPLA3 genotype and …

Y Seko, Y Sumida, S Tanaka, K Mori… - Hepatology …, 2017 - Wiley Online Library
Aim Some patients with non‐alcoholic fatty liver disease (NAFLD) develop hepatocellular
carcinoma (HCC). Patatin‐like phospholipase domain containing 3 (PNPLA3) rs738409 …

Development and validation of a scoring system, based on genetic and clinical factors, to determine risk of steatohepatitis in Asian patients with nonalcoholic fatty liver …

BK Koo, SK Joo, D Kim, S Lee, JM Bae, JH Park… - Clinical …, 2020 - Elsevier
Background & Aims There are no biomarkers of nonalcoholic steatohepatitis (NASH) that
are ready for routine clinical use. We investigated whether an analysis of PNPLA3 and …

Association of the I148M/PNPLA3 (rs738409) polymorphism with premature coronary artery disease, fatty liver, and insulin resistance in type 2 diabetic patients and …

R Posadas-Sánchez, ÁR López-Uribe… - Immunobiology, 2017 - Elsevier
The aim of this study was to evaluate the potential use of the I148M/PNPLA3 (rs738409)
gene polymorphism as a susceptibility marker for premature coronary artery disease (pCAD) …