Neutrophils and platelets are among the most abundant cell types in peripheral blood and
characterized by high plasticity and a readily available reservoir of surface proteins and …

NETosis is a multi-facetted cellular process that promotes the formation of neutrophil
extracellular traps (NETs). NETs as web-like structures consist of DNA fibers armed with …

Over the past 10 years, neutrophil extracellular traps (NETs) have become widely accepted
as an integral player in immunothrombosis, due to their complex interplay with both …

Infective endocarditis (IE) is a life-threatening infective disease with increasing incidence
worldwide. From early on, in the antibiotic era, it was recognized that high-dose and long …

Background: Infective endocarditis (IE) is characterized by an infected thrombus at the heart
valves. How bacteria bypass the immune system and cause these thrombi remains unclear …

Staphylococcus aureus (S. aureus) is a leading human pathogen capable of producing
severe invasive infections such as bacteremia, sepsis, and endocarditis with high morbidity …

Over the last decade, the incidence of infective endocarditis (IE) has increased, with a
change in the frequency of causative bacteria. Early evidence has substantially …

Neutrophils, as innate effector cells, play an essential role in the containment and
elimination of pathogens. Among the main neutrophil mechanisms use for these processes …

Platelets have a well-recognized role in hemostasis and thrombosis, and they are important
amplifiers of inflammation and innate immune responses. The formation of DNA extracellular …

Neutrophil extracellular traps (NETs) are web-like structures of decondensed extracellular
chromatin fibers and neutrophil granule proteins released by neutrophils. NETs participate …