[HTML][HTML] The impact of SARS-CoV-2 infection on the development of neurodegeneration in multiple sclerosis

A Dziedzic, J Saluk-Bijak, E Miller… - International Journal of …, 2021 - mdpi.com
The novel coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), remains a global challenge. Currently …

[HTML][HTML] Histamine H4 receptor antagonist ameliorates the progression of experimental autoimmune encephalomyelitis via regulation of T-cell imbalance

AA Aldossari, MA Assiri, MA Ansari, A Nadeem… - International Journal of …, 2023 - mdpi.com
Multiple sclerosis (MS) is a degenerative condition characterized by immune-mediated
attacks on the central nervous system (CNS), resulting in demyelination and recurring T-cell …

[HTML][HTML] Abnormal oxidative metabolism in the cuprizone mouse model of demyelination: An in vivo NIRS-MRI study

M Hashem, Q Shafqat, Y Wu, JM Rho, JF Dunn - Neuroimage, 2022 - Elsevier
Disruptions in oxidative metabolism may occur in multiple sclerosis and other demyelinating
neurological diseases. The impact of demyelination on metabolic rate is also not …

Neuroimmune signaling at the brain borders

NM Frederick, GA Tavares… - Immunological Reviews, 2022 - Wiley Online Library
The central nervous system (CNS) has been viewed as an immunologically privileged site,
but emerging works are uncovering a large array of neuroimmune interactions primarily …

The effects of modified curcumin preparations on glial morphology in aging and neuroinflammation

F Ullah, R Gamage, MK Sen, E Gyengesi - Neurochemical Research, 2022 - Springer
Neuroinflammation is characterized by reactive microglia and astrocytes (collectively called
gliosis) in the central nervous system and is considered as one of the main pathological …

[HTML][HTML] Epigenomic priming of immune genes implicates oligodendroglia in multiple sclerosis susceptibility

M Meijer, E Agirre, M Kabbe, CA van Tuijn, A Heskol… - Neuron, 2022 - cell.com
Multiple sclerosis (MS) is characterized by a targeted attack on oligodendroglia (OLG) and
myelin by immune cells, which are thought to be the main drivers of MS susceptibility. We …

[HTML][HTML] Histological and top-down proteomic analyses of the visual pathway in the cuprizone demyelination model

MSM Almuslehi, MK Sen, PJ Shortland… - Journal of Molecular …, 2022 - Springer
A change in visual perception is a frequent early symptom of multiple sclerosis (MS), the
pathoaetiology of which remains unclear. Following a slow demyelination process caused …

[HTML][HTML] The emerging roles of piezo1 channels in animal models of multiple sclerosis

K Yang, X He, Z Wu, Y Yin, H Pan, X Zhao… - Frontiers in …, 2022 - frontiersin.org
Multiple sclerosis (MS) is a chronic inflammatory, demyelinating, and neurodegenerative
disease in the central nervous system (CNS). Its pathogenesis is quite complex …

[HTML][HTML] The Heterogeneous Multiple Sclerosis Lesion: How Can We Assess and Modify a Degenerating Lesion?

O Ellen, S Ye, D Nheu, M Dass, M Pagnin… - International Journal of …, 2023 - mdpi.com
Multiple sclerosis (MS) is a heterogeneous disease of the central nervous system that is
governed by neural tissue loss and dystrophy during its progressive phase, with complex …

[HTML][HTML] Brain volume loss can occur at the rate of normal aging in patients with multiple sclerosis who are free from disease activity

J Temmerman, F Van Der Veken… - Journal of Clinical …, 2022 - mdpi.com
Multiple sclerosis (MS) is a chronic inflammatory demyelinating and degenerative disorder
of the central nervous system. Accelerated brain volume loss (BVL) has emerged as a …