Polyunsaturated fatty acids and fatty acid-derived lipid mediators: Recent advances in the understanding of their biosynthesis, structures, and functions

SC Dyall, L Balas, NG Bazan, JT Brenna… - Progress in lipid …, 2022 - Elsevier
Polyunsaturated fatty acids (PUFAs) are structural components of membrane phospholipids,
and influence cellular function via effects on membrane properties, and also by acting as a …

Effects of dietary n–3 and n–6 polyunsaturated fatty acids in inflammation and cancerogenesis

KP Liput, A Lepczyński, M Ogłuszka… - International journal of …, 2021 - mdpi.com
The dietary recommendation encourages reducing saturated fatty acids (SFA) in diet and
replacing them with polyunsaturated fatty acids (PUFAs) n–3 (omega–3) and n–6 (omega …

Update on LIPID MAPS classification, nomenclature, and shorthand notation for MS-derived lipid structures

G Liebisch, E Fahy, J Aoki, EA Dennis, T Durand… - Journal of lipid …, 2020 - ASBMB
A comprehensive and standardized system to report lipid structures analyzed by MS is
essential for the communication and storage of lipidomics data. Herein, an update on both …

Oxidation of polyunsaturated fatty acids to produce lipid mediators

WW Christie, JL Harwood - Essays in biochemistry, 2020 - portlandpress.com
The chemistry, biochemistry, pharmacology and molecular biology of oxylipins (defined as a
family of oxygenated natural products that are formed from unsaturated fatty acids by …

[HTML][HTML] Metabolite discovery: Biochemistry's scientific driver

M Giera, O Yanes, G Siuzdak - Cell metabolism, 2022 - cell.com
Metabolite identification represents a major challenge, and opportunity, for biochemistry.
The collective characterization and quantification of metabolites in living organisms, with its …

[HTML][HTML] Monitoring wastewater for assessing community health: Sewage Chemical-Information Mining (SCIM)

CG Daughton - Science of The Total Environment, 2018 - Elsevier
Timely assessment of the aggregate health of small-area human populations is essential for
guiding the optimal investment of resources needed for preventing, avoiding, controlling, or …

Poultry meat and eggs as an alternative source of n-3 long-chain polyunsaturated fatty acids for human nutrition

A Cartoni Mancinelli, S Mattioli, C Twining, A Dal Bosco… - Nutrients, 2022 - mdpi.com
The beneficial effects of n-3 long-chain polyunsaturated fatty acids (n-3 LC-PUFA) on human
health are widely known. Humans are rather inefficient in synthesizing n-3 LC-PUFA; thus …

Lipid peroxidation in atherosclerotic cardiovascular diseases

E Gianazza, M Brioschi… - Antioxidants & redox …, 2021 - liebertpub.com
Significance: Atherosclerotic cardiovascular diseases (ACVDs) continue to be a primary
cause of mortality worldwide in adults aged 35–70 years, occurring more often in countries …

Polyunsaturated fatty acids: conversion to lipid mediators, roles in inflammatory diseases and dietary sources

JL Harwood - International Journal of Molecular Sciences, 2023 - mdpi.com
Polyunsaturated fatty acids (PUFAs) are important components of the diet of mammals. Their
role was first established when the essential fatty acids (EFAs) linoleic acid and α-linolenic …

Lipid peroxidation and antioxidant supplementation in neurodegenerative diseases: a review of human studies

S Petrovic, A Arsic, D Ristic-Medic, Z Cvetkovic, V Vucic - Antioxidants, 2020 - mdpi.com
Being characterized by progressive and severe damage in neuronal cells,
neurodegenerative diseases (NDDs) are the major cause of disability and morbidity in the …