Cardiovascular diseases (CVDs) are the leading cause of human mortality worldwide.
Oxidative stress and inflammation are pathophysiological processes involved in the …

Background and Purpose: Population-wide reductions in cardiovascular disease incidence
and mortality have not been shared equally by African Americans. The burden of …

In this guideline, the World Health Organization (WHO) provides the most current and
relevant evidence-based global public health guidance on the initiation of treatment with …

Background Raised blood pressure is an important risk factor for cardiovascular diseases
and chronic kidney disease. We estimated worldwide trends in mean systolic and mean …

Background Treatment inertia is a recognised barrier to blood pressure control, and simpler,
more effective treatment strategies are needed. We hypothesised that a hypertension …

Hypertension affects two-thirds of people aged> 60 years and significantly increases the risk
of both vascular cognitive impairment and Alzheimer's disease. Hypertension compromises …

Polygenic scores (PGS) have been widely used to predict disease risk using variants
identified from genome-wide association studies (GWAS). To date, most GWAS have been …

The global nephrology community recognises the need for a cohesive plan to address the
problem of chronic kidney disease (CKD). In July, 2016, the International Society of …

Gut microbiota produce Trimethylamine N-oxide (TMAO) by metabolizing dietary
phosphatidylcholine, choline, l-carnitine and betaine. TMAO is implicated in the …

Background Primary headache disorders are common and burdensome conditions. They
are associated to several comorbidities, such as cardiovascular or psychiatric ones, which …