Noncoding RNAs as regulators of STAT3 pathway in gastrointestinal cancers: Roles in cancer progression and therapeutic response

M Ashrafizadeh, CD Mohan… - Medicinal research …, 2023 - Wiley Online Library
Gastrointestinal (GI) tumors (cancers of the esophagus, gastric, liver, pancreas, colon, and
rectum) contribute to a large number of deaths worldwide. STAT3 is an oncogenic …

STAT3 pathway in cancers: Past, present, and future

HQ Wang, QW Man, FY Huo, X Gao, H Lin, SR Li… - MedComm, 2022 - Wiley Online Library
Signal transducer and activator of transcription 3 (STAT3), a member of the STAT family,
discovered in the cytoplasm of almost all types of mammalian cells, plays a significant role in …

CircDIDO1 inhibits gastric cancer progression by encoding a novel DIDO1-529aa protein and regulating PRDX2 protein stability

Y Zhang, J Jiang, J Zhang, H Shen, M Wang, Z Guo… - Molecular cancer, 2021 - Springer
Abstract Background Circular RNAs (circRNAs) play important roles in cancer development
and progression. The purpose of this study is to identify aberrantly expressed circRNAs in …

Natural compounds targeting glycolysis as promising therapeutics for gastric cancer: a review

M Zhao, F Wei, G Sun, Y Wen, J Xiang, F Su… - Frontiers in …, 2022 - frontiersin.org
Gastric cancer, a common malignant disease, seriously endangers human health and life.
The high mortality rate due to gastric cancer can be attributed to a lack of effective …

Circular RNAs: emerging regulators of the major signaling pathways involved in cancer progression

M Papatsirou, PI Artemaki, P Karousi, A Scorilas… - Cancers, 2021 - mdpi.com
Simple Summary Circular RNAs (circRNAs) are single-stranded RNA molecules that form a
covalently closed loop structure. They are characterized by distinct features and …

Angelica sinensis Polysaccharide and Astragalus membranaceus Polysaccharide Accelerate Liver Regeneration by Enhanced Glycolysis via Activation of JAK2 …

XD Wen, YL Zhang, L Yang, Z Ye, GC Fu, YH Hu… - Molecules, 2022 - mdpi.com
The promotion of liver regeneration is crucial to avoid liver failure after hepatectomy.
Angelica sinensis polysaccharide (ASP) and Astragalus membranaceus polysaccharide …

[HTML][HTML] Circular RNAs: emerging regulators of glucose metabolism in cancer

ZR Cai, Y Hu, K Liao, H Li, DL Chen, HQ Ju - Cancer Letters, 2023 - Elsevier
Aberrant glucose metabolism is one of the most striking characteristics of metabolic
reprogramming in cancer. Thus, clarifying the regulatory mechanism of glucose metabolism …

[Retracted] PCBP2 Reduced Oxidative Stress‐Induced Apoptosis in Glioma through cGAS/STING Pathway by METTL3‐Mediated m6A Modification

X Chen, M Yu, W Xu, P Kun, W Wan… - Oxidative Medicine …, 2022 - Wiley Online Library
Purpose. The most prevalent primary malignant tumor of CNS is glioma, which has a dismal
prognosis. The theory of oxidative stress is one of the important theories in the study of its …

[Retracted] Human Umbilical Cord Mesenchymal Stem Cells Improve Premature Ovarian Failure through Cell Apoptosis of miR‐100‐5p/NOX4/NLRP3

J Niu, F Yu, X Luo, S Chen - BioMed Research International, 2022 - Wiley Online Library
Premature ovarian failure refers to a series of symptoms of perimenopausal hot flashes,
night sweats, decreased libido, vaginal dryness, insomnia, reduced menstruation, sparse …

CircC16orf62 promotes hepatocellular carcinoma progression through the miR-138-5p/PTK2/AKT axis

S Zhang, Y Lu, HY Jiang, ZM Cheng, ZJ Wei… - Cell Death & …, 2021 - nature.com
Circular RNA (circRNAs) functions vital in the pathogenesis and progression of
hepatocellular carcinoma (HCC). However, the expressions and functions of certain …