In developing countries, acquired bacterial resistance to antimicrobial agents is common in
isolates from healthy persons and from persons with community-acquired infections …

The euphoria produced by the discovery of antibiotics led to confident predictions that
bacterial diseases would soon be conquered and could thus be safely forgotten, leaving …

The intense use and misuse of antibiotics are undoubtedly the major forces associated with
the high numbers of resistant pathogenic and commensal bacteria worldwide. Both the …

The human intestine is an important location for horizontal gene transfer (HGT) due to the
presence of a densely populated community of microorganisms which are essential to the …

The increase in bacterial antibiotic resistance is of major concern worldwide, but pertinent
epidemiologic studies have used strongly divergent approaches and are widely scattered in …

Antimicrobial agents are associated with side-effects, which are usually tolerated because
the benefits of treatment outweigh the toxic effects. Clinicians know about these side-effects …

Antimicrobial resistance may become a major problem in veterinary medicine as a
consequence of the intensive use and misuse of antimicrobial drugs. Related problems are …

Using a rapid screening method, we investigated the prevalence of fecal carriage of
antimicrobial drug–resistant Escherichia coli in 3,174 healthy children from 4 urban settings …

The ecological impact of antibiotic resistance in the absence of selective pressure has been
poorly studied. We assessed the carriage of tetracycline resistance genes, persistence in the …

Extended-spectrum β-lactamase (ESBL)-mediated resistance is of considerable importance
in human medicine. Recently, such enzymes have been reported in bacteria from animals …