Extracellular vesicles (EVs) are released from all cells in the body, forming an important
intercellular communication network that contributes to health and disease. The contents of …

The release of membrane-bound vesicles from cells is being increasingly recognized as a
mechanism of intercellular communication. Extracellular vesicles (EVs) or exosomes are …

The RNA modification N6-methyladenosine (m 6 A) post-transcriptionally regulates RNA
function. The cellular machinery that controls m 6 A includes methyltransferases and …

Programmable nucleases have enabled rapid and accessible genome engineering in
eukaryotic cells and living organisms. However, their delivery into target cells can be …

Many aspects of the hepatitis C virus (HCV) life cycle have not been reproduced in cell
culture, which has slowed research progress on this important human pathogen. Here, we …

The absence of a robust cell culture model of hepatitis C virus (HCV) infection has severely
limited analysis of the HCV life cycle and the development of effective antivirals and …

Hepatitis C virus (HCV) is a leading cause of cirrhosis and liver cancer worldwide. A better
understanding of the viral life cycle, including the mechanisms of entry into host cells, is …

Hepatitis C virus (HCV) is a major cause of liver diseases including liver cirrhosis and
hepatocellular carcinoma. Approximately 3% of the world population is infected with HCV …

Among the many viruses that are known to infect the human liver, hepatitis B virus (HBV)
and hepatitis C virus (HCV) are unique because of their prodigious capacity to cause …

Extracellular vesicles (EVs), or exosomes, are nanovesicles of endocytic origin that carry
host and pathogen-derived protein, nucleic acid, and lipid cargos. They are secreted by …