A comprehensive review on barium titanate nanoparticles as a persuasive piezoelectric material for biomedical applications: prospects and challenges

A Sood, M Desseigne, A Dev, L Maurizi, A Kumar… - Small, 2023 - Wiley Online Library
Stimulation of cells with electrical cues is an imperative approach to interact with biological
systems and has been exploited in clinical practices over a wide range of pathological …

Electrical stimulation system based on electroactive biomaterials for bone tissue engineering

X Zhang, T Wang, Z Zhang, H Liu, L Li, A Wang… - Materials Today, 2023 - Elsevier
Traumatic injuries can lead to large bone defects under extreme conditions, which usually
take a long recovery period, while the prognosis is poor. Endogenous electric field, as one …

[HTML][HTML] A biomimetic piezoelectric scaffold with sustained Mg2+ release promotes neurogenic and angiogenic differentiation for enhanced bone regeneration

L Wang, Y Pang, Y Tang, X Wang, D Zhang, X Zhang… - Bioactive Materials, 2023 - Elsevier
Natural bone is a composite tissue made of organic and inorganic components, showing
piezoelectricity. Whitlockite (WH), which is a natural magnesium-containing calcium …

[HTML][HTML] Improving bone regeneration with composites consisting of piezoelectric poly (L-lactide) and piezoelectric calcium/manganese co-doped barium titanate …

T Zheng, Y Yu, Y Pang, D Zhang, Y Wang… - Composites Part B …, 2022 - Elsevier
The reconstruction of the local electrical microenvironment at the defect site has been
considered as an effective strategy in stimulating bone regeneration. To mimic the …

Materials‐Mediated In Situ Physical Cues for Bone Regeneration

S Liu, L Zhang, Z Li, F Gao, Q Zhang… - Advanced Functional …, 2024 - Wiley Online Library
Physical cues like morphology, light, electric signal, mechanic signal, magnetic signal, and
heat can be used as alternative regulators for expensive but short‐acting growth factors in …

Additive manufacturing of barium-doped calcium silicate/poly-ε-caprolactone scaffolds to activate CaSR and AKT signalling and osteogenic differentiation of …

YC Chiu, YH Lin, YW Chen, TY Kuo… - Journal of Materials …, 2023 - pubs.rsc.org
3D-printed scaffolds are suitable for patient-specific implant preparation for bone
regeneration in large-scale critical bone defects. In addition, these scaffolds should have …

Enhanced cell osteogenesis and osteoimmunology regulated by piezoelectric biomaterials with controllable surface potential and charges

L Mao, L Bai, X Wang, X Chen, D Zhang… - … Applied Materials & …, 2022 - ACS Publications
Bone regeneration is a well-orchestrated process involving electrical, biochemical, and
mechanical multiple physiological cues. Electrical signals play a vital role in the process of …

Integrated piezoelectric/conductive composite cryogel creates electroactive microenvironment for enhanced bone regeneration

T Zheng, Y Pang, D Zhang, Y Wang… - Advanced …, 2023 - Wiley Online Library
Natural bone tissue possesses inherent electrophysiological characteristics, displaying
conductivity and piezoelectricity simultaneously; hence, the reconstruction of local electrical …

Advanced strategies of scaffolds design for bone regeneration

J Song, L Li, L Fang, E Zhang, Y Zhang, Z Zhang… - …, 2023 - Wiley Online Library
Bone defects are encountered substantially in clinical practice, and bionic scaffolds
represent a promising solution for repairing bone defects. However, it is difficult to fabricate …

Ceramic nanofiber materials for wound healing and bone regeneration: a brief review

D dos Santos Gomes, R de Sousa Victor, BV de Sousa… - Materials, 2022 - mdpi.com
Ceramic nanofibers have been shown to be a new horizon of research in the biomedical
area, due to their differentiated morphology, nanoroughness, nanotopography, wettability …