Gasotransmitters in cancer: from pathophysiology to experimental therapy
C Szabo - Nature reviews Drug discovery, 2016 - nature.com
The three endogenous gaseous transmitters—nitric oxide (NO), carbon monoxide (CO) and
hydrogen sulfide (H2S)—regulate a number of key biological functions. Emerging data have …
hydrogen sulfide (H2S)—regulate a number of key biological functions. Emerging data have …
Reactive species from cold atmospheric plasma: Implications for cancer therapy
DB Graves - Plasma Processes and Polymers, 2014 - Wiley Online Library
Cold atmospheric plasmas (CAP) formed in air generate reactive oxygen and nitrogen
species (RONS). RONS are biologically and therapeutically active agents and experimental …
species (RONS). RONS are biologically and therapeutically active agents and experimental …
Hydrogen sulfide: an emerging precision strategy for gas therapy
H Ding, J Chang, F He, S Gai… - Advanced Healthcare …, 2022 - Wiley Online Library
Advances in nanotechnology have enabled the rapid development of stimuli‐responsive
therapeutic nanomaterials for precision gas therapy. Hydrogen sulfide (H2S) is a significant …
therapeutic nanomaterials for precision gas therapy. Hydrogen sulfide (H2S) is a significant …
New techniques and strategies in drug discovery
J Du, J Guo, D Kang, Z Li, G Wang, J Wu, Z Zhang… - Chinese Chemical …, 2020 - Elsevier
Great success has been witnessed in last decades, some new techniques and strategies
have been widely used in drug discovery. In this roadmap, several representative …
have been widely used in drug discovery. In this roadmap, several representative …
State of the art, challenges and perspectives in the design of nitric oxide-releasing polymeric nanomaterials for biomedical applications
Recently, an increasing number of publications have demonstrated the importance of the
small molecule nitric oxide (NO) in several physiological and pathophysiological processes …
small molecule nitric oxide (NO) in several physiological and pathophysiological processes …
[HTML][HTML] Nitric oxide-mediated sensitization of resistant tumor cells to apoptosis by chemo-immunotherapeutics
B Bonavida, H Garban - Redox biology, 2015 - Elsevier
The generation of NO by the various NO synthases in normal and malignant tissues is
manifested by various biological effects that are involved in the regulation of cell survival …
manifested by various biological effects that are involved in the regulation of cell survival …
Anti-Cancer Activities of Diterpenoids Derived from Euphorbia fischeriana Steud
B Jian, H Zhang, C Han, J Liu - Molecules, 2018 - mdpi.com
Euphorbia fischeriana Steud is an essential oriental folk medicine used for healing cancer,
edema and tuberculosis. Recently, its anticancer activitity has attracted more attention. A …
edema and tuberculosis. Recently, its anticancer activitity has attracted more attention. A …
Two-dimensional (2D) hybrid nanomaterials for diagnosis and treatment of cancer
Incessant rising in morbidity and mortality rates in humans due to various types of cancers
requires effective treatments and early-stage diagnosis. The chemotherapy is typically …
requires effective treatments and early-stage diagnosis. The chemotherapy is typically …
Anti-CD24 antibody–nitric oxide conjugate selectively and potently suppresses hepatic carcinoma
F Sun, Y Wang, X Luo, Z Ma, Y Xu, X Zhang, T Lv… - Cancer research, 2019 - AACR
Nitric oxide (NO) has a wide range of potential applications in tumor therapy. However, a
targeted delivery system for NO donors has remained elusive, creating a bottleneck that …
targeted delivery system for NO donors has remained elusive, creating a bottleneck that …
Nitric oxide releasing nanomaterials for cancer treatment: current status and perspectives
Nitric oxide (NO) is known to have dichotomous effects on cancer biology, acting as a pro-or
antineoplastic agent. Low concentrations of NO are reported to promote tumor growth …
antineoplastic agent. Low concentrations of NO are reported to promote tumor growth …