The sleep-immune crosstalk in health and disease

L Besedovsky, T Lange, M Haack - Physiological reviews, 2019 - journals.physiology.org
Sleep-immune interactions are well-known phenomena in everyday life and folk wisdom.
There is no doubt that an infection makes us tired and increases the desire to sleep, and a …

Decreased serum brain-derived neurotrophic factor (BDNF) levels in patients with Alzheimer's disease (AD): a systematic review and meta-analysis

TKS Ng, CSH Ho, WWS Tam, EH Kua… - International journal of …, 2019 - mdpi.com
Findings from previous studies reporting the levels of serum brain-derived neurotrophic
factor (BDNF) in patients with Alzheimer's disease (AD) and individuals with mild cognitive …

Cerebral hypoperfusion and glucose hypometabolism: Key pathophysiological modulators promote neurodegeneration, cognitive impairment, and Alzheimer's …

MA Daulatzai - Journal of neuroscience research, 2017 - Wiley Online Library
Aging, hypertension, diabetes, hypoxia/obstructive sleep apnea (OSA), obesity, vitamin
B12/folate deficiency, depression, and traumatic brain injury synergistically promote diverse …

[HTML][HTML] Neuroinflammation, sleep, and circadian rhythms

MR Zielinski, AJ Gibbons - Frontiers in cellular and infection …, 2022 - frontiersin.org
Molecules involved in innate immunity affect sleep and circadian oscillators and vice versa.
Sleep-inducing inflammatory molecules are activated by increased waking activity and …

[HTML][HTML] Functions and mechanisms of sleep

MR Zielinski, JT McKenna, RW McCarley - AIMS neuroscience, 2016 - ncbi.nlm.nih.gov
Sleep is a complex physiological process that is regulated globally, regionally, and locally
by both cellular and molecular mechanisms. It occurs to some extent in all animals, although …

Gut microbiota changes and their relationship with inflammation in patients with acute and chronic insomnia

Y Li, B Zhang, Y Zhou, D Wang, X Liu, L Li… - Nature and science of …, 2020 - Taylor & Francis
Purpose The major purpose of this study was to detect the changes in gut microbiota
composition and inflammatory cytokines production associated with acute and chronic …

The role of adenosine receptors in mood and anxiety disorders

D van Calker, K Biber, K Domschke… - Journal of …, 2019 - Wiley Online Library
Adenosine receptor subtypes, first described 40 years ago, are known to regulate diverse
biological functions and have a role in various conditions, such as cerebral and cardiac …

The brain-derived neurotrophic factor: missing link between sleep deprivation, insomnia, and depression

M Rahmani, F Rahmani, N Rezaei - Neurochemical research, 2020 - Springer
The brain-derived neurotrophic factor (BDNF) mediates the plasticity-related changes that
associate with memory processing during sleep. Sleep deprivation and chronic stress are …

[HTML][HTML] Neuroplasticity and clinical practice: Building brain power for health

J Shaffer - Frontiers in psychology, 2016 - frontiersin.org
The focus of this review is on driving neuroplasticity in a positive direction using evidence-
based interventions that also have the potential to improve general health. One goal is to …

Peripheral brain-derived neurotrophic factor (BDNF) in insomnia: A systematic review and meta-analysis

A Ballesio, A Zagaria, DG Curti, R Moran… - Sleep medicine …, 2023 - Elsevier
The brain-derived neurotrophic factor (BDNF) is associated with emotional and cognitive
functioning, and it is considered a transdiagnostic biomarker for mental disorders. Literature …