[HTML][HTML] Inflammatory links between obesity and metabolic disease

CN Lumeng, AR Saltiel - The Journal of clinical …, 2011 - Am Soc Clin Investig
The obesity epidemic has forced us to evaluate the role of inflammation in the health
complications of obesity. This has led to a convergence of the fields of immunology and …

[HTML][HTML] Crosstalk in NF-κB signaling pathways

A Oeckinghaus, MS Hayden, S Ghosh - Nature immunology, 2011 - nature.com
NF-κB transcription factors are critical regulators of immunity, stress responses, apoptosis
and differentiation. A variety of stimuli coalesce on NF-κB activation, which can in turn …

Role of gut microbiota in chronic low‐grade inflammation as potential driver for atherosclerotic cardiovascular disease: a systematic review of human studies

ICL van den Munckhof, A Kurilshikov… - Obesity …, 2018 - Wiley Online Library
A hallmark of obesity is chronic low‐grade inflammation, which plays a major role in the
process of atherosclerotic cardiovascular disease (ACVD). Gut microbiota is one of the …

[HTML][HTML] Cytochrome P450: polymorphisms and roles in cancer, diabetes and atherosclerosis

I Elfaki, R Mir, FM Almutairi… - Asian Pacific journal of …, 2018 - ncbi.nlm.nih.gov
Cytochromes P450s (CYPs) constitute a superfamily of enzymes that catalyze the
metabolism of drugs and other substances. Endogenous substrates of CYPs include …

[HTML][HTML] AMP-activated protein kinase (AMPK) controls the aging process via an integrated signaling network

A Salminen, K Kaarniranta - Ageing research reviews, 2012 - Elsevier
Efficient control of energy metabolic homeostasis, enhanced stress resistance, and qualified
cellular housekeeping are the hallmarks of improved healthspan and extended lifespan …

The blood-testis barrier and its implications for male contraception

CY Cheng, DD Mruk - Pharmacological reviews, 2012 - ASPET
The blood-testis barrier (BTB) is one of the tightest blood-tissue barriers in the mammalian
body. It divides the seminiferous epithelium into the basal and the apical (adluminal) …

[HTML][HTML] Global trends in research of macrophages associated with acute lung injury over past 10 years: a bibliometric analysis

S Wang, H Zhou, L Zheng, W Zhu, L Zhu… - Frontiers in …, 2021 - frontiersin.org
Acute lung injury (ALI) is an intractable disorder associated with macrophages. This
bibliometric analysis was applied to identify the characteristics of global scientific output, the …

Acupuncture Attenuates Inflammation in Microglia of Vascular Dementia Rats by Inhibiting miR‐93‐Mediated TLR4/MyD88/NF‐κB Signaling Pathway

L Wang, JW Yang, LT Lin, J Huang… - Oxidative Medicine …, 2020 - Wiley Online Library
Background. It is widely accepted that inflammation may contribute to cognitive impairment
in patients with vascular dementia (VD). Our prior clinical researches have reported that …

Association between obesity, inflammation and insulin resistance: Insights into signaling pathways and therapeutic interventions

SS Garg, K Kushwaha, R Dubey, J Gupta - Diabetes research and clinical …, 2023 - Elsevier
Obesity, a metabolic disorder, is becoming a worldwide epidemic that predominantly
increases the risk for various diseases including metabolic inflammation, insulin resistance …

The triumvirate of NF-κB, inflammation and cytokine storm in COVID-19

A Attiq, LJ Yao, S Afzal, MA Khan - International immunopharmacology, 2021 - Elsevier
Abstract The coronavirus disease (COVID-19) has once again reminded us of the
significance of host immune response and consequential havocs of the immune …