Regioselective Synthesis of 7-(Trimethylsilylethynyl)pyrazolo[1,5-a]pyrimidines via Reaction of Pyrazolamines with Enynones
P Golubev, EA Karpova, AS Pankova… - The Journal of …, 2016 - ACS Publications
Condensation of enynones readily available from cheap starting material with
pyrazolamines provides easy access to fluorescent 7-(trimethylsilylethynyl) pyrazolo [1, 5-a] …
pyrazolamines provides easy access to fluorescent 7-(trimethylsilylethynyl) pyrazolo [1, 5-a] …
An assessment study of known pyrazolopyrimidines: Chemical methodology and cellular activity
Heterocyclic compounds with nitrogen atom play a key role in the normal life cycle of a cell.
Pyrazolopyrimidine is a privileged class of nitrogen containing fused heterocyclic compound …
Pyrazolopyrimidine is a privileged class of nitrogen containing fused heterocyclic compound …
Design, synthesis, cytotoxicity and molecular modeling studies of some novel fluorinated pyrazole-based heterocycles as anticancer and apoptosis-inducing agents
Diamino-4-(3-trifluoromethylphenyldiazenyl)-1 H-pyrazole was used as a starting scaffold for
the synthesis of new pyrazole-based heterocycles to study their effects on the proliferation of …
the synthesis of new pyrazole-based heterocycles to study their effects on the proliferation of …
Regioselective one-pot synthesis and anti-proliferative and apoptotic effects of some novel tetrazolo [1, 5-a] pyrimidine derivatives
AM Hussein, OM Ahmed - Bioorganic & medicinal chemistry, 2010 - Elsevier
An easy and efficient route for the synthesis of some tetrazolo [1, 5-a]-pyrimidine derivatives
was described through the reaction of sodium salts of formyl cycloalkanones with 5 …
was described through the reaction of sodium salts of formyl cycloalkanones with 5 …
Synthesis and in-vitro anti-proliferative evaluation of some pyrazolo [1, 5-a] pyrimidines as novel larotrectinib analogs
Abstract A series of 2-phenyl-7-(aryl) pyrazolo [1, 5-a] pyrimidine-3-carbonitriles 11a–j and 2-
phenyl-7-(aryl) pyrazolo [1, 5-a] pyrimidine-3, 6-dicarbonitriles 16a–c was synthesized by …
phenyl-7-(aryl) pyrazolo [1, 5-a] pyrimidine-3, 6-dicarbonitriles 16a–c was synthesized by …
[HTML][HTML] Application of novel metal–organic frameworks containing sulfonic acid pendings in synthesis of chromeno [4, 3-d] pyrimidines via back to back anomeric …
F Jalili, H Sepehrmansourie, M Zarei… - Arabian Journal of …, 2024 - Elsevier
Through task-specific design and synthesis of mesoporous catalysts, we introduce a novel
metal–organic framework serving as a heterogeneous catalyst. In this study, Co (BDC-NH …
metal–organic framework serving as a heterogeneous catalyst. In this study, Co (BDC-NH …
Carbon–Carbon Bond Cleavage Reaction: Synthesis of Multisubstituted Pyrazolo[1,5-a]pyrimidines
P Saikia, S Gogoi, RC Boruah - The Journal of Organic Chemistry, 2015 - ACS Publications
A new carbon–carbon bond cleavage reaction was developed for the efficient synthesis of
multisubstituted pyrazolo [1, 5-a] pyrimidines. This base induced reaction of 1, 3, 5 …
multisubstituted pyrazolo [1, 5-a] pyrimidines. This base induced reaction of 1, 3, 5 …
Design, synthesis, docking, and antimicrobial evaluation of some novel pyrazolo[1,5-a] pyrimidines and their corresponding cycloalkane ring-fused derivatives as …
AEM Abdallah, GH Elgemeie - drug design, development and …, 2018 - Taylor & Francis
Background Over the years, pyrazolopyrimidine derivatives have been recognized as
having antimicrobial activities. Recently, we reported different synthetic methods to prepare …
having antimicrobial activities. Recently, we reported different synthetic methods to prepare …
Synthesis and Anti-inflammatory Evaluation of Some New Pyrazole, Pyrimidine, Pyrazolo[1,5-a]Pyrimidine, Imidazo[1,2-b]Pyrazole and Pyrazolo[5,1-b]Quinazoline …
EH El-Sayed, KS Mohamed - Polycyclic Aromatic Compounds, 2021 - Taylor & Francis
A new series of pyrazole, pyrimidine, pyrazolo [1, 5-a] pyrimidine, imidazo [1, 2-b] pyrazole
and pyrazolo [5, 1-b] quinazoline derivatives containing indane moiety are prepared by …
and pyrazolo [5, 1-b] quinazoline derivatives containing indane moiety are prepared by …
Bis(benzofuran-enaminone) hybrid possessing piperazine linker: Versatile precursor for microwave assisted synthesis of bis(pyrido[2',3':3,4]pyrazolo[1,5-a] …
We reported herein efficient procedures for the synthesis of new piperazine-linked bis
(pyrido [2', 3': 3, 4] pyrazolo [1, 5-a] pyrimidines) using bis (benzofuran-enaminone) hybrid …
(pyrido [2', 3': 3, 4] pyrazolo [1, 5-a] pyrimidines) using bis (benzofuran-enaminone) hybrid …