Abstract New 7-hydroxy-6-phenyl-3-(phenyldiazenyl) pyrazolo [1, 5-a] pyrimidine-2, 5 (1H,
4H)-dione derivatives were synthesized from the reaction of (chlorocarbonyl) phenyl ketene …

The present study deals with a highly efficient and regioselective synthesis of 7-aryl-5-
methyl-and 5-aryl-7-trifluoromethyl-2-amino-3-(4′-arylazo)-pyrazolo [1, 5-a] pyrimidines via …

Seven new complexes of2-oxo-4, 6-diphenyl-1, 2-dihyropyridine-3-carbonitrile (L) with Fe
(III), Co (II), Cu (II), Zn (II), Y (III), Zr (IV) and La (III) were synthesized. The isolated solid …

Amino-1-phenyl-1 H-pyrazole-4-carbohydraizde (1) was used as a key to synthesize new
imidazopyrazol-5 (1 H)-one 5, pyrazolopyrimidines 7 and 9. Furthermore, imidazopyrazoles …

2016-06-27 Assigned to VERTEX PHARMACEUTICALS (EUROPE) LIMITED reassignment
VERTEX PHARMACEUTICALS (EUROPE) LIMITED ASSIGNMENT OF ASSIGNORS …

Abstract Substituted 1H-pyrazolo [3, 4-b] pyridine-4-and 1H-pyrazolo [3, 4-b] pyridine-6-
carboxamides have been synthetized through a Doebner–Ugi multicomponent reaction …

An eco-friendly and metal-free method for the synthesis of tetrahydrodibenzo [b, g][1, 8]
naphthyridin-1 (2H)-ones was established. Quinoline-derived dipolarophiles and cyclic …

For anticancer cell line evaluation, a new sequence of pyrazolo [1-5a] pyrimidine and
imidazo [1, 2-b] pyrazole derivatives were synthesized. The reaction of 5-aminopyrazolo with …

2-(4-Oxo-1-phenyl-4, 5-dihydro-1H-pyrazolo [3, 4-d] pyrimidin-6-yl) acetonitrile was used as
the key intermediate for the synthesis of polyfunctionally substituted heterocycles (eg …

The reaction of polyfluoroalkyl-containing 2-tolylhydrazinylidene-1, 3-diketones with 3-
aminopyrazoles depending on their structure can proceed as N, N-cyclization to form 5-R F …