Crystallographic structures of NGF/p75NTR and proNGF/p75NTR were previously obtained
in 2: 1 and 2: 2 stoichiometries, respectively. However, evidence shows that both …

Since the discovery of nerve growth factor, there has been accumulating evidence that
neurotrophins (NTs) mediate various biological responses of peripheral and central …

Dogs are a major source of indoor allergens. However, the prevalence of dog allergies in
China remains unclear, especially in children. In the present study, Can f 7, a canine …

Brain-derived neurotrophic factor (BDNF) is a neurotrophin that elicits neuronal survival and
differentiation, synaptic transmission, and the modulation of synaptic plasticity. The …

Mature sympathetic neurons in the superior cervical ganglion (SCG) are regulated by target-
derived neurotrophins such as nerve growth factor (NGF) and neurotrophin-3 (NT-3). High …

Snake neurotoxins are short all-β proteins that display a complex organization of the
disulfide bonds: two bonds connect consecutive cysteine residues (C43− C54, C55− C60) …

Protein folding can be modulated in vivo by many factors. While chaperones act as folding
catalysts and show broad substrate specificity, some pro‐peptides specifically facilitate the …

Age-related neurodegenerative diseases, such as Alzheimer's disease, will represent one of
the largest future burdens on worldwide healthcare systems due to the increasing proportion …

We have shown previously that nerve growth factor (NGF) requires only low nanomolar ATP
concentrations in the cell culture medium to protect cortical rat neurons (CRN) from cellular …