Implementation of international guidelines for the treatment of epileptic spasms, is
challenging when access to adrenocorticotrophic hormone (ACTH) and vigabatrin is …

Abstract Background In children with West syndrome (WS), whose treatment is challenging
due to drug resistance and poor prognosis, investigation of genetic etiology and genotype …

Vigabatrin is one of the second-generation anti-seizure medications (ASMs) designated
orphan drugs by the FDA for monotherapy for pediatric patients with infantile spasms from 1 …

Infantile spasms (IS) is a devastating epilepsy syndrome that typically begins in the first year
of life. Symptoms consist of stereotypical spasms, developmental delay, and …

Background This study aimed to investigate and analyze the risk factors for non-etiology-
specific infantile spasms (IS) and unrelieved clinical symptoms after treatment. Methods …

ACTH, a melanocortin peptide used to treat multiple sclerosis (MS) relapses, acts by
stimulating adrenal corticosteroid (CS) production via melanocortin receptor 2 (MC2R), but it …

Covering neuroimaging evidence has demonstrated that epileptic symptoms are associated
with the disrupted topological architecture of the brain network. Infantile spasms (IS) as an …

Background: Infantile spasms are an age-specific epileptic disorder. They occur in infancy
and early childhood. They can be caused by multiple etiologies. Structural abnormalities …

Cannabinoid compounds have therapeutic properties, but also psychotropic effects.
Cannabidiol (CBD) extracted from Cannabis sativa has been used in cases of epilepsy, a …

Objective The aim of this study was to investigate attachment behavior in a population of
infants with infantile spasms (ISs) using the Strange Situation Procedure (SSP) and to …