Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …

Hepatic macrophages play a central role in maintaining homeostasis in the liver, as well as
in the initiation and progression of liver diseases. Hepatic macrophages are mainly derived …

This study investigates the protective effect of baicalein on carbon tetrachloride (CCl4)-
induced acute liver injury and the underlying molecular mechanisms. Mice were orally …

This is the first study to investigate the hepatoprotective effect of CQ on acute liver injury
caused by carbon tetrachloride (CCl4) in a murine model and the underlying molecular …

The liver is sensitive to pathogen-induced acute or chronic liver injury, and liver
transplantation (LT) is the only effective strategy for end-stage liver diseases. However, the …

Curcumin, the natural yellow‐colored active principle, also called turmeric yellow, extracted
from the perennial herb Curcuma longa L., has potent biological and pharmacological …

Different etiologies such as drug toxicity, acute viral hepatitis B, or acetaminophen poisoning
can cause acute liver injury or even acute liver failure (ALF). Excessive cell death of …

There has been increasing interest in pyroptosis as a novel form of pro-inflammatory
programmed cell death. The mechanism of pyroptosis is significantly different from other …

Drug toxicity is frequently caused by electrophilic reactive metabolites that covalently bind to
proteins. Epoxides comprise a large class of three-membered cyclic ethers. These …

The clinical phenotype of classical autoimmune hepatitis can be mimicked by idiosyncratic
drug-induced liver injury, and differentiation can be difficult. The goals of this review are to …