Heart failure with preserved ejection fraction: mechanisms, clinical features, and therapies
The clinical syndrome comprising heart failure (HF) symptoms but with a left ventricular
ejection fraction (EF) that is not diminished, eg, HF with preserved EF, is increasingly the …
ejection fraction (EF) that is not diminished, eg, HF with preserved EF, is increasingly the …
What mechanisms underlie diastolic dysfunction in heart failure?
Abnormalities of diastolic function are common to virtually all forms of cardiac failure.
However, their underlying mechanisms, precise role in the generation and phenotypic …
However, their underlying mechanisms, precise role in the generation and phenotypic …
Combined ventricular systolic and arterial stiffening in patients with heart failure and preserved ejection fraction: implications for systolic and diastolic reserve …
M Kawaguchi, I Hay, B Fetics, DA Kass - Circulation, 2003 - Am Heart Assoc
Background—Heart failure with preserved ejection fraction (HF-nlEF) is common in aged
individuals with systolic hypertension and is frequently ascribed to diastolic dysfunction. We …
individuals with systolic hypertension and is frequently ascribed to diastolic dysfunction. We …
Effect of aging and physical activity on left ventricular compliance
A Arbab-Zadeh, E Dijk, A Prasad, Q Fu, P Torres… - Circulation, 2004 - Am Heart Assoc
Background—Left ventricular compliance appears to decrease with aging, which may
contribute to the high incidence of heart failure in the elderly. However, whether this change …
contribute to the high incidence of heart failure in the elderly. However, whether this change …
Effect of age on mortality, hospitalizations and response to digoxin in patients with heart failure: the DIG study
MW Rich, F McSherry, WO Williford, S Yusuf… - Journal of the American …, 2001 - jacc.org
OBJECTIVES This study was designed to determine the effect of increasing age on mortality,
hospitalizations and digoxin side effects in patients with heart failure (HF), and to determine …
hospitalizations and digoxin side effects in patients with heart failure (HF), and to determine …
Exercise training in systolic and diastolic dysfunction: effects on cardiac function, functional capacity, and quality of life
N Smart, B Haluska, L Jeffriess, TH Marwick - American heart journal, 2007 - Elsevier
BACKGROUND: Exercise training improves functional capacity in patients with systolic
dysfunction (SD), but the role of exercise training in diastolic dysfunction (DD) is unclear. We …
dysfunction (SD), but the role of exercise training in diastolic dysfunction (DD) is unclear. We …
Age-related changes in venticular–arterial coupling: pathophysiologic implications
DA Kass - Heart failure reviews, 2002 - Springer
The interaction of the heart with the systemic vasculature, termed ventricular–arterial
coupling, is a central determinant of net cardiovascular performance. The capacity of the …
coupling, is a central determinant of net cardiovascular performance. The capacity of the …
[HTML][HTML] Stress-induced premature senescence is associated with a prolonged QT interval and recapitulates features of cardiac aging
E Lazzarini, AM Lodrini, M Arici, S Bolis, S Vagni… - Theranostics, 2022 - ncbi.nlm.nih.gov
Rationale: Aging in the heart is a gradual process, involving continuous changes in
cardiovascular cells, including cardiomyocytes (CMs), namely cellular senescence. These …
cardiovascular cells, including cardiomyocytes (CMs), namely cellular senescence. These …
Effect of nurse‐implemented transitional care for Chinese individuals with chronic heart failure in Hong Kong: A randomized controlled trial
Objectives To determine the effect of nurse‐implemented transitional care (TC) on
readmission and mortality rates in Chinese individuals with chronic heart failure (CHF) in …
readmission and mortality rates in Chinese individuals with chronic heart failure (CHF) in …
Cardiorespiratory fitness and reclassification of risk for incidence of heart failure: the veterans exercise testing study
J Myers, P Kokkinos, K Chan, E Dandekar… - Circulation: heart …, 2017 - Am Heart Assoc
Background—It is well established that cardiorespiratory fitness (CRF) is inversely
associated with cardiovascular and all-cause mortality. However, little is known regarding …
associated with cardiovascular and all-cause mortality. However, little is known regarding …