The clinical syndrome comprising heart failure (HF) symptoms but with a left ventricular
ejection fraction (EF) that is not diminished, eg, HF with preserved EF, is increasingly the …

Abnormalities of diastolic function are common to virtually all forms of cardiac failure.
However, their underlying mechanisms, precise role in the generation and phenotypic …

Background—Heart failure with preserved ejection fraction (HF-nlEF) is common in aged
individuals with systolic hypertension and is frequently ascribed to diastolic dysfunction. We …

Background—Left ventricular compliance appears to decrease with aging, which may
contribute to the high incidence of heart failure in the elderly. However, whether this change …

OBJECTIVES This study was designed to determine the effect of increasing age on mortality,
hospitalizations and digoxin side effects in patients with heart failure (HF), and to determine …

BACKGROUND: Exercise training improves functional capacity in patients with systolic
dysfunction (SD), but the role of exercise training in diastolic dysfunction (DD) is unclear. We …

The interaction of the heart with the systemic vasculature, termed ventricular–arterial
coupling, is a central determinant of net cardiovascular performance. The capacity of the …

Rationale: Aging in the heart is a gradual process, involving continuous changes in
cardiovascular cells, including cardiomyocytes (CMs), namely cellular senescence. These …

Objectives To determine the effect of nurse‐implemented transitional care (TC) on
readmission and mortality rates in Chinese individuals with chronic heart failure (CHF) in …

Background—It is well established that cardiorespiratory fitness (CRF) is inversely
associated with cardiovascular and all-cause mortality. However, little is known regarding …