Pushing the envelope: LPS modifications and their consequences
BW Simpson, MS Trent - Nature Reviews Microbiology, 2019 - nature.com
The defining feature of the Gram-negative cell envelope is the presence of two cellular
membranes, with the specialized glycolipid lipopolysaccharide (LPS) exclusively found on …
membranes, with the specialized glycolipid lipopolysaccharide (LPS) exclusively found on …
Pathogenesis of Helicobacter pylori Infection
JG Kusters, AHM Van Vliet… - Clinical microbiology …, 2006 - Am Soc Microbiol
Helicobacter pylori is the first formally recognized bacterial carcinogen and is one of the
most successful human pathogens, as over half of the world's population is colonized with …
most successful human pathogens, as over half of the world's population is colonized with …
[HTML][HTML] Dietary suppression of MHC class II expression in intestinal epithelial cells enhances intestinal tumorigenesis
Little is known about how interactions of diet, intestinal stem cells (ISCs), and immune cells
affect early-stage intestinal tumorigenesis. We show that a high-fat diet (HFD) reduces the …
affect early-stage intestinal tumorigenesis. We show that a high-fat diet (HFD) reduces the …
Overexpression of interleukin-1β induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice
S Tu, G Bhagat, G Cui, S Takaishi, EA Kurt-Jones… - Cancer cell, 2008 - cell.com
Polymorphisms of interleukin-1β (IL-1β) are associated with an increased risk of solid
malignancies. Here, we show that stomach-specific expression of human IL-1β in transgenic …
malignancies. Here, we show that stomach-specific expression of human IL-1β in transgenic …
Coadaptation of Helicobacter pylori and humans: ancient history, modern implications
JC Atherton, MJ Blaser - The Journal of clinical investigation, 2009 - Am Soc Clin Investig
Humans have been colonized by Helicobacter pylori for at least 50,000 years and probably
throughout their evolution. H. pylori has adapted to humans, colonizing children and …
throughout their evolution. H. pylori has adapted to humans, colonizing children and …
Lipopolysaccharide detection by the innate immune system may be an uncommon defence strategy used in nature
Since the publication of the Janeway's Pattern Recognition hypothesis in 1989, study of
pathogen-associated molecular patterns (PAMPs) and their immuno-stimulatory activities …
pathogen-associated molecular patterns (PAMPs) and their immuno-stimulatory activities …
Heterogeneity of lipopolysaccharide as source of variability in bioassays and LPS-binding proteins as remedy
AC Fux, C Casonato Melo, S Michelini… - International Journal of …, 2023 - mdpi.com
Lipopolysaccharide (LPS), also referred to as endotoxin, is the major component of Gram-
negative bacteria's outer cell wall. It is one of the main types of pathogen-associated …
negative bacteria's outer cell wall. It is one of the main types of pathogen-associated …
Bacterial membrane vesicles deliver peptidoglycan to NOD1 in epithelial cells
Gram‐negative bacterial peptidoglycan is specifically recognized by the host intracellular
sensor NOD1, resulting in the generation of innate immune responses. Although epithelial …
sensor NOD1, resulting in the generation of innate immune responses. Although epithelial …
Structural modifications of bacterial lipopolysaccharide that facilitate gram-negative bacteria evasion of host innate immunity
M Matsuura - Frontiers in immunology, 2013 - frontiersin.org
Bacterial lipopolysaccharide (LPS), a cell wall component characteristic of Gram-negative
bacteria, is a representative pathogen-associated molecular pattern that allows mammalian …
bacteria, is a representative pathogen-associated molecular pattern that allows mammalian …
Role of the Helicobacter pylori‐Induced inflammatory response in the development of gastric cancer
A Lamb, LF Chen - Journal of cellular biochemistry, 2013 - Wiley Online Library
Helicobacter pylori (H. pylori) infection causes chronic gastritis and peptic ulceration and is
the strongest risk factor for the development of gastric cancer. The pathogenesis of H. pylori …
the strongest risk factor for the development of gastric cancer. The pathogenesis of H. pylori …