Apoptotic cell-derived exosomes: messages from dying cells

R Kakarla, J Hur, YJ Kim, J Kim… - Experimental & Molecular …, 2020 - nature.com
Apoptosis, a type of programmed cell death that plays a key role in both healthy and
pathological conditions, releases extracellular vesicles such as apoptotic bodies and …

Progress of engineered bacteria for tumor therapy

JX Fan, MT Niu, YT Qin, YX Sun, XZ Zhang - Advanced Drug Delivery …, 2022 - Elsevier
Recently, with the rapid development of bioengineering technology and nanotechnology,
natural bacteria were modified to change their physiological activities and therapeutic …

Lymphocytopenia and neutrophil-lymphocyte count ratio predict bacteremia better than conventional infection markers in an emergency care unit

CPC de Jager, PTL van Wijk, RB Mathoera… - Critical care, 2010 - Springer
Introduction Absolute lymphocytopenia has been reported as a predictor of bacteremia in
medical emergencies. Likewise, the neutrophil-lymphocyte count ratio (NLCR) has been …

The neutrophil-lymphocyte count ratio in patients with community-acquired pneumonia

CPC de Jager, PC Wever, EFA Gemen, R Kusters… - 2012 - journals.plos.org
Study Objective The neutrophil-lymphocyte count ratio (NLCR) has been identified as a
predictor of bacteremia in medical emergencies. The aim of this study was to investigate the …

Molecular mechanisms of biogenesis of apoptotic exosome-like vesicles and their roles as damage-associated molecular patterns

SJ Park, JM Kim, J Kim, J Hur, S Park… - Proceedings of the …, 2018 - National Acad Sciences
Recent research has led to contradictory notions regarding the conventional theory that
apoptotic cell death can evoke inflammatory or immunogenic responses orchestrated by …

Relation between lymphopenia and bacteraemia in UK adults with medical emergencies

DH Wyllie, I Bowler, TEA Peto - Journal of clinical pathology, 2004 - jcp.bmj.com
Aims: To determine the relevance of lymphopenia to the diagnosis of bacteraemia in
patients admitted with medical emergencies, relative to peripheral blood white cell count …

Protective role of angiopoietin-1 in endotoxic shock

B Witzenbichler, D Westermann, S Knueppel… - Circulation, 2005 - Am Heart Assoc
Background—Angiopoietin-1 (Ang1) plays an essential role in embryonic vasculature
development, protects the adult peripheral vasculature from leakage, and has …

Pleiotropic effects for Parkin and LRRK2 in leprosy type-1 reactions and Parkinson's disease

VM Fava, YZ Xu, G Lettre, N Van Thuc… - Proceedings of the …, 2019 - National Acad Sciences
Type-1 reactions (T1R) are pathological inflammatory episodes and main contributors to
nerve damage in leprosy. Here, we evaluate the genewise enrichment of rare protein …

Baicalin improves survival in a murine model of polymicrobial sepsis via suppressing inflammatory response and lymphocyte apoptosis

J Zhu, J Wang, Y Sheng, Y Zou, L Bo, F Wang, J Lou… - PloS one, 2012 - journals.plos.org
Background An imbalance between overwhelming inflammation and lymphocyte apoptosis
is the main cause of high mortality in patients with sepsis. Baicalin, the main active …

Effects of preanalytical variables on peptide and protein measurements in human serum and plasma: implications for clinical proteomics

AJ Rai, F Vitzthum - Expert review of proteomics, 2006 - Taylor & Francis
There is a wealth of knowledge in the field of in vitro diagnostics with regard to preanalytical
variables and their impact on the determination of peptide and protein analytes in human …