Statistical and methodological considerations for the interpretation of intranasal oxytocin studies
Over the last decade, oxytocin (OT) has received focus in numerous studies associating
intranasal administration of this peptide with various aspects of human social behavior …
intranasal administration of this peptide with various aspects of human social behavior …
Does oxytocin increase trust in humans? A critical review of research
Behavioral neuroscientists have shown that the neuropeptide oxytocin (OT) plays a key role
in social attachment and affiliation in nonhuman mammals. Inspired by this initial research …
in social attachment and affiliation in nonhuman mammals. Inspired by this initial research …
Effects of route of administration on oxytocin-induced changes in regional cerebral blood flow in humans
DA Martins, N Mazibuko, F Zelaya… - Nature …, 2020 - nature.com
Could nose-to-brain pathways mediate the effects of peptides such as oxytocin (OT) on brain
physiology when delivered intranasally? We address this question by contrasting two …
physiology when delivered intranasally? We address this question by contrasting two …
Links between the neurobiology of oxytocin and human musicality
AR Harvey - Frontiers in human neuroscience, 2020 - frontiersin.org
The human species possesses two complementary, yet distinct, universal communication
systems—language and music. Functional imaging studies have revealed that some core …
systems—language and music. Functional imaging studies have revealed that some core …
Oxytocin and social functioning
C Jones, I Barrera, S Brothers, R Ring… - Dialogues in clinical …, 2017 - Taylor & Francis
Social anxiety is a form of anxiety characterized by continuous fear of one or more social or
performance situations. Although multiple treatment modalities (cognitive behavioral …
performance situations. Although multiple treatment modalities (cognitive behavioral …
Oxytocin delivered nasally or intraperitoneally reaches the brain and plasma of normal and oxytocin knockout mice
Intranasal delivery of oxytocin (Oxt) has been identified as a potential therapeutic to target
human conditions characterized by social deficits, yet the ability of this administrative route …
human conditions characterized by social deficits, yet the ability of this administrative route …
Social decision-making and the brain: A comparative perspective
The capacity and motivation to be social is a key component of the human adaptive
behavioral repertoire. Recent research has identified social behaviors remarkably similar to …
behavioral repertoire. Recent research has identified social behaviors remarkably similar to …
Agile delivery of protein therapeutics to CNS
X Yi, DS Manickam, A Brynskikh… - Journal of Controlled …, 2014 - Elsevier
A variety of therapeutic proteins have shown potential to treat central nervous system (CNS)
disorders. Challenge to deliver these protein molecules to the brain is well known. Proteins …
disorders. Challenge to deliver these protein molecules to the brain is well known. Proteins …
A review of oxytocin's effects on the positive, negative, and cognitive domains of schizophrenia
D Feifel, PD Shilling, K MacDonald - Biological psychiatry, 2016 - Elsevier
Schizophrenia is a disabling, heterogeneous disorder with clinical features that can be
parsed into three domains: positive symptoms, negative symptoms, and cognitive deficits …
parsed into three domains: positive symptoms, negative symptoms, and cognitive deficits …
Interplay between the oxytocin and opioid systems in regulating social behaviour
The influence of neuromodulators on brain activity and behaviour is undeniably profound,
yet our knowledge of the underlying mechanisms, or ability to reliably reproduce effects …
yet our knowledge of the underlying mechanisms, or ability to reliably reproduce effects …