[HTML][HTML] Neurocircuitry of addiction

GF Koob, ND Volkow - Neuropsychopharmacology, 2010 - nature.com
Drug addiction is a chronically relapsing disorder that has been characterized by (1)
compulsion to seek and take the drug,(2) loss of control in limiting intake, and (3) emergence …

Smoking and increased Alzheimer's disease risk: a review of potential mechanisms

TC Durazzo, N Mattsson, MW Weiner… - Alzheimer's & …, 2014 - Wiley Online Library
Background Cigarette smoking has been linked with both increased and decreased risk for
Alzheimer's disease (AD). This is relevant for the US military because the prevalence of …

Neural substrates of smoking cue reactivity: a meta-analysis of fMRI studies

JM Engelmann, F Versace, JD Robinson, JA Minnix… - Neuroimage, 2012 - Elsevier
Reactivity to smoking-related cues may be an important factor that precipitates relapse in
smokers who are trying to quit. The neurobiology of smoking cue reactivity has been …

The genetic epidemiology of substance use disorder: A review

EC Prom-Wormley, J Ebejer, DM Dick… - Drug and alcohol …, 2017 - Elsevier
Background Substance use disorder (SUD) remains a significant public health issue. A
greater understanding of how genes and environment interact to regulate phenotypes …

Brain stress systems in the amygdala and addiction

GF Koob - Brain research, 2009 - Elsevier
Dysregulation of the brain emotional systems that mediate arousal and stress is a key
component of the pathophysiology of drug addiction. Drug addiction is a chronically …

Developmental toxicity of nicotine: a transdisciplinary synthesis and implications for emerging tobacco products

LJ England, K Aagaard, M Bloch, K Conway… - Neuroscience & …, 2017 - Elsevier
While the health risks associated with adult cigarette smoking have been well described,
effects of nicotine exposure during periods of developmental vulnerability are often …

[HTML][HTML] Chronic cigarette smoking: implications for neurocognition and brain neurobiology

TC Durazzo, DJ Meyerhoff, SJ Nixon - International journal of …, 2010 - mdpi.com
Compared to the substantial volume of research on the general health consequences
associated with chronic smoking, little research has been specifically devoted to the …

The co‐occurrence of cigarette smoking and bipolar disorder: phenomenology and treatment considerations

JL Heffner, JR Strawn, MP DelBello… - Bipolar …, 2011 - Wiley Online Library
Heffner JL, Strawn JR, DelBello MP, Strakowski SM, Anthenelli RM. The co‐occurrence of
cigarette smoking and bipolar disorder: phenomenology and treatment considerations …

Abuse liability assessment of tobacco products including potential reduced exposure products

LP Carter, ML Stitzer, JE Henningfield… - … Biomarkers & Prevention, 2009 - AACR
The harm produced by tobacco products is a result of frequent use of a highly toxic product.
Reducing the adverse public health impact of tobacco products might be most effectively …

Neural correlates of craving and resisting craving for tobacco in nicotine dependent smokers

KJ Hartwell, KA Johnson, X Li, H Myrick… - Addiction …, 2011 - Wiley Online Library
Craving is a significant factor which can lead to relapse during smoking quit attempts.
Attempts to resist urges to smoke during cue‐elicited craving have been shown to activate …