Osteoporosis is a common skeletal disease, affecting~ 200 million people around the world.
As a complex disease, osteoporosis is influenced by many factors, including diet (eg calcium …

Macrophages are specialized cells that control tissue homeostasis. They include non-
resident and tissue-resident macrophage populations which are characterized by the …

Long-chain polyunsaturated fatty acids (LCPUFAs) and their metabolites are considered
essential factors to support bone and joint health. The n-6 PUFAs suppress the osteoblasts …

Skeletal tissue development and regeneration in mammals are intricate, multistep, and
highly regulated processes. Various signaling pathways have been implicated in the …

Osteoclasts, the only cells with bone resorption functions in vivo, maintain the balance of
bone metabolism by cooperating with osteoblasts, which are responsible for bone formation …

Besides the classical ones (support/protection, hematopoiesis, storage for calcium, and
phosphate) multiple roles emerged for bone tissue, definitively making it an organ …

Osteosarcoma (OS) is the predominant primary bone tumor in the pediatric and adolescent
populations. It has high metastatic potential, with the lungs being the most common site of …

Calcific aortic valve disease (CAVD), previously thought to represent a passive
degeneration of the valvular extracellular matrix (VECM), is now regarded as an intricate …

The skeleton is the framework and in charge of body configuration preservation. As a living
tissue, bones are constantly being formed and absorbed. Osteoblasts and osteoclasts are …

Objective: Osteoimmunology investigates interactions between skeleton and immune
system. In the light of recent discoveries in this field, a new reading register of osteoporosis …