The diagnosis of drug-induced liver injury (DILI) is a challenging problem, often confounded
by incomplete clinical information and the difficulty of eliciting exposure to herbal products …

Background Chemotherapy-associated liver injury is a major cause for concern when
treating patients with colorectal liver metastases. The aim of this review was to determine the …

A key challenge for improving the efficacy of passive drug delivery to tumor sites by a
nanocarrier is to limit reticuloendothelial system uptake and to maximize the enhanced …

Purpose Oxaliplatin-based chemotherapy can cause hepatic sinusoidal injury, with resultant
sinusoidal damage and portal hypertension. We sought to explore the relationship between …

Oxaliplatin (OXA) is a third-generation platinum anticancer drug that is mainly used for the
treatment of metastatic colorectal cancer (CRC). Of note, hepatic sinusoidal obstruction …

Background The impact of chemotherapy-associated liver injury (CALI) on postoperative
outcome in patients undergoing partial hepatectomy for colorectal liver metastases (CRLM) …

Background Chemotherapy-induced liver injury is a considerable problem in patients
undergoing surgery for colorectal liver metastases, since an increase in postoperative …

AIM: In patients suffering from colorectal cancer liver metastases, 5-fluorouracil-based
chemotherapy plus oxaliplatin ensures superior response rates at the cost of hepatic injury …

Patients with colorectal cancer (CRC) have benefited significantly from advances in
multimodal treatment with significant improvements in long-term survival. More patients are …

Objective To assess whether reticular hypointensity on hepatobiliary phase images of
gadoxetic acid-enhanced magnetic resonance imaging (EOB-MRI) is a diagnostic finding of …