Almost 2 billion adults in the world are overweight, and more than half of them are classified
as obese, while nearly one-third of children globally experience poor growth and …

Dr David Barker first popularized the concept of fetal origins of adult disease (FOAD). Since
its inception, FOAD has received considerable attention. The FOAD hypothesis holds that …

The implications for research and clinical practice are discussed with a summary of recent
advances in noninvasive methods to characterize fetal, newborn, infant, and child …

Epidemiological, clinical, physiological, cellular, and molecular evidence suggests that the
origins of obesity and metabolic dysfunction can be traced back to intrauterine life and …

These examples serve to provide perspective on the potential harm that man-made
obesogenic pollutants pose to human health, focus attention on areas in which knowledge …

Cardiovascular disease (CVD) is a leading cause of death globally, with the prevalence
projected to keep rising. Risk factors for adult CVD emerge at least as early as the prenatal …

Background Accumulating evidence reveals that intrauterine growth retardation (IUGR) can
cause varying degrees of pulmonary arterial hypertension (PAH) later in life. Moreover …

For several years now, the epidemiological data have shown an inverse relationship
between birth-weight and the development in later life of cardiovascular disease and …

Intrauterine growth‐restricted (IUGR) newborns have increased risk of adult metabolic
syndrome, including fatty liver. However, it is unclear whether the fatty liver development is …

One hundred and fifty years ago, Paul Langerhans described what would come to be known
as pancreatic 'islet of Langerhans'. Since then, we have accumulated knowledge about the …