Fentanyl for breakthrough pain: a systematic review
MP Davis - Expert review of neurotherapeutics, 2011 - Taylor & Francis
The purpose of this article is to systematically review the use of fentanyl as an analgesic for
breakthrough pain. This article found that the oral transmucosal fentanyl (OTFC) had a …
breakthrough pain. This article found that the oral transmucosal fentanyl (OTFC) had a …
Cultivation of RPMI 2650 cells as an in-vitro model for human transmucosal nasal drug absorption studies: optimization of selected culture conditions
S Reichl, K Becker - Journal of Pharmacy and Pharmacology, 2012 - academic.oup.com
Objectives The kinetics of drug absorption for nasally administered drugs are often studied
using excised mucosal tissue. To avoid the disadvantages of animal experiments, cellular in …
using excised mucosal tissue. To avoid the disadvantages of animal experiments, cellular in …
The Path from Nasal Tissue to Nasal Mucosa on Chip: Part 1—Establishing a Nasal In Vitro Model for Drug Delivery Testing Based on a Novel Cell Line
S Bendas, EV Koch, K Nehlsen, T May, A Dietzel… - Pharmaceutics, 2023 - mdpi.com
In recent years, there has been a significant increase in the registration of drugs for nasal
application with systemic effects. Previous preclinical in vitro test systems for transmucosal …
application with systemic effects. Previous preclinical in vitro test systems for transmucosal …
Assessment of Drug–Drug Interaction Risk Between Intravenous Fentanyl and the Glecaprevir/Pibrentasvir Combination Regimen in Hepatitis C Patients Using …
D Mukherjee, M Collins, DE Dylla, J Kaur… - Infectious Diseases and …, 2023 - Springer
Introduction An unsafe injection practice is one of the major contributors to new hepatitis C
virus (HCV) infections; thus, people who inject drugs are a key population to prioritize to …
virus (HCV) infections; thus, people who inject drugs are a key population to prioritize to …
Opioid‐induced hypogonadism: pathophysiology, clinical and therapeutics review
T Antony, SY Alzaharani… - Clinical and …, 2020 - Wiley Online Library
Opioids are pivotal therapeutics in the management of escalated chronic pain (moderate–
severe). In the last two decades, the increased prescription rate and the prolonged usage of …
severe). In the last two decades, the increased prescription rate and the prolonged usage of …
Intranasal fentanyl in the treatment of acute pain–a systematic review
MS Hansen, O Mathiesen, S Trautner… - Acta …, 2012 - Wiley Online Library
Due to its non‐invasive mode of administration, intranasal (IN) application of drugs may be a
valuable alternative to non‐invasive pain management. With characteristics that appear to …
valuable alternative to non‐invasive pain management. With characteristics that appear to …
Intranasal fentanyl: from pharmacokinetics and bioavailability to current treatment applications
I Panagiotou, K Mystakidou - Expert review of anticancer therapy, 2010 - Taylor & Francis
Fentanyl, a short-acting synthetic pure opiate, offers an excellent option for the treatment of
cancer and chronic pain. While oral administration is not an option, its high potency and …
cancer and chronic pain. While oral administration is not an option, its high potency and …
Assessment and treatment of breakthrough cancer pain: from theory to clinical practice
R Vellucci, RD Mediati, S Gasperoni… - Journal of pain …, 2017 - Taylor & Francis
Breakthrough cancer pain (BTcP) is a common condition in oncological patients. However,
its management is still suboptimal. Improved knowledge of BTcP and its management in …
its management is still suboptimal. Improved knowledge of BTcP and its management in …
Equivalency of two concentrations of fentanyl administered by the intranasal route for acute analgesia in children in a paediatric emergency department: a randomized …
M Borland, S Milsom, A Esson - Emergency Medicine …, 2011 - Wiley Online Library
Objective: Intranasal fentanyl's (INF) effectiveness is established using highly concentrated
INF (HINF). Standard concentration INF (SINF) is more widely available. We aimed to …
INF (HINF). Standard concentration INF (SINF) is more widely available. We aimed to …
Intranasal fentanyl for initial treatment of vaso‐occlusive crisis in sickle cell disease
Background Analgesia administration for children with vaso‐occlusive crises is often
delayed in the emergency department. Intranasal fentanyl (INF) has been shown to be safe …
delayed in the emergency department. Intranasal fentanyl (INF) has been shown to be safe …